SCHEMBL6737669

SCHEMBL6737669

CCCc1ccc2cc3cc(F)c(F)c(F)c3cc2c1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CNR1 P21554 1/20 0.39
CNR2 P34972 1/20 0.39
CYP1A2 P05177 1/20 0.37
CYP2A6 P11509 1/20 0.37
NCEH1 Q6PIU2 2/20 0.33
ALOX5 P09917 1/20 0.32
NPC1 O15118 1/20 0.31
TP53 P04637 1/20 0.31
PKM P14618 1/20 0.31
RAB9A P51151 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
HSD17B10 Q99714 1/20 0.31
SIGMAR1 Q99720 1/20 0.31
BDKRB2 P30411 1/20 0.31
MEN1 O00255 1/20 0.31
POLB P06746 1/20 0.31
GAA P10253 1/20 0.31
KMT2A Q03164 1/20 0.31
CYP19A1 P11511 1/20 0.31
THRB P10828 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6738566 1.00 CNR1 (0.39) CNR1CNR2CYP1A2CYP2A6NCEH1
SCHEMBL6736230 0.91 SKP2 (0.37) CYP1A2CYP2A6SIGMAR1BDKRB2GRIN2D
SCHEMBL6734879 0.91 SKP2 (0.37) CYP1A2CYP2A6SIGMAR1BDKRB2GRIN2D
SCHEMBL6741483 0.90 HTR2A (0.39) TP53HSD17B10BDKRB2SLC6A2SLC6A4
SCHEMBL6735680 0.89 CYP1A2 (0.48) CYP1A2CYP2A6NPC1RAB9ASMN1; SMN2
SCHEMBL6736398 0.89 CYP1A2 (0.48) CYP1A2CYP2A6NPC1RAB9ASMN1; SMN2
SCHEMBL6741865 0.86 CNR1 (0.38) CNR1CNR2CYP1A2CYP2A6NCEH1
SCHEMBL6736746 0.85 CNR1 (0.37) CNR1CNR2CYP1A2CYP2A6NCEH1
SCHEMBL6731332 0.82 TLR8 (0.35) CNR1CNR2NCEH1ALOX5SIGMAR1
SCHEMBL6731268 0.82 CYP1A2 (0.42) CNR1CNR2CYP1A2CYP2A6ALOX5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6682785-B2 A FLUOROANTHRACENE COMPOUNDS; HEAT RESISTANCE, RADIATION RESISTANCE, PHOTOSTABILITY CLARIANT FINANCE (BVI) LIMITED (VG) 2004-01-27 US disclosed
US-20030118749-A1 A fluoroanthracene compounds; heat resistance, radiation resistance, photostability CLARIANT INTERNATIONAL LTD. 2003-06-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030118749-A1 A fluoroanthracene compounds; heat resistance, radiation resistance, photostability HSF1, ABCC1, FLNA CNR1 2742/4885CNR2 3959/4885CYP1A2 80/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.