Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | TSHR | P16473 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.43 |
| ▸ | ACHE | P22303 | 2/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.42 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.41 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL309875 | 0.85 | LMNA (0.49) | ALDH1A1KDM4EPOLBKMT2ATSHR | |
| SCHEMBL21416735 | 0.83 | LMNA (0.59) | TSHRCYP3A4PIK3CACYP2D6SIGMAR1 | |
| SCHEMBL3722909 | 0.83 | CYP2A13 (0.61) | ALDH1A1KDM4EKMT2AMEN1CYP3A4 | |
| SCHEMBL13293671 | 0.82 | ALDH1A1 (0.54) | ALDH1A1KDM4EPOLBKMT2ATSHR | |
| SCHEMBL2912056 | 0.82 | ALDH1A1 (0.61) | ALDH1A1KDM4EPOLBKMT2AMEN1 | |
| SCHEMBL21400926 | 0.80 | KMT2A (0.53) | ALDH1A1KDM4EPOLBKMT2ATSHR | |
| SCHEMBL1641681 | 0.80 | ALDH1A1 (0.58) | ALDH1A1KDM4EPOLBKMT2AMEN1 | |
| SCHEMBL18190467 | 0.79 | ALDH1A1 (0.51) | ALDH1A1KDM4EPOLBKMT2ATSHR | |
| SCHEMBL10315553 | 0.79 | ALDH1A1 (0.59) | ALDH1A1KDM4EPOLBCYP2D6CYP2C19 | |
| SCHEMBL30341017 | 0.79 | ALDH1A1 (0.69) | ALDH1A1KDM4EPOLBKMT2ATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040127507-A1 | Imidazolidine compounds | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2004-07-01 | — | — | US | disclosed |
| US-20040122026-A1 | Imidazolidine compounds | MILLENNIUM PHARMACEUTICALS, INC. | 2004-06-24 | — | — | US | disclosed |
| US-20030225288-A1 | Imidazolidine compounds | MILLENNIUM PHARMACEUTICALS, INC. | 2003-12-04 | — | — | US | disclosed |
| WO-2003087063-A1 | IMIDAZOLIDINE COMPOUNDS AS CHEMOKINE RECEPTOR MODULATORS | KYOWA HAKKO KOGYO CO., LTD. (JP) | 2003-10-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040127507-A1 | Imidazolidine compounds | IRAK1, IRAK4, IRAK2 | ALDH1A1 569/4885KDM4E 4423/4885POLB 3185/4885 |
| US-20030225288-A1 | Imidazolidine compounds | IRAK1, IRAK4, IRAK2 | ALDH1A1 569/4885KDM4E 4423/4885POLB 3185/4885 |
| US-20040122026-A1 | Imidazolidine compounds | IRAK1, IRAK4, IRAK2 | ALDH1A1 569/4885KDM4E 4423/4885POLB 3185/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.