Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 1/20 | 0.51 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | CASP3 | P42574 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.39 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.39 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 5/20 | 0.37 |
| ▸ | PTGS1 | P23219 | 5/20 | 0.37 |
| ▸ | EGFR | P00533 | 1/20 | 0.37 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6730112 | 0.83 | PTPN1 (0.57) | PTPN1CA1CA2NPC1LMNA | |
| SCHEMBL6734019 | 0.80 | PTPN1 (0.53) | PTPN1CA1CA2NPC1LMNA | |
| SCHEMBL3695040 | 0.77 | PTPN1 (0.62) | PTPN1CA1CA2NPC1LMNA | |
| SCHEMBL3694407 | 0.74 | PTPN1 (0.59) | PTPN1CA1CA2NPC1LMNA | |
| SCHEMBL3690533 | 0.74 | PTPN1 (0.59) | PTPN1CA1CA2NPC1LMNA | |
| SCHEMBL3692501 | 0.73 | MAPT (0.59) | PTPN1CA1CA2NPC1LMNA | |
| SCHEMBL3692020 | 0.73 | PTPN1 (0.61) | PTPN1CA1CA2NPC1LMNA | |
| SCHEMBL3692363 | 0.70 | PTPN1 (0.45) | PTPN1CA1CA2MEN1GAA | |
| SCHEMBL3687863 | 0.69 | PTPN1 (0.57) | PTPN1CA1CA2NPC1LMNA | |
| SCHEMBL31006760 | 0.69 | CA2 (0.67) | PTPN1CA1CA2SMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040152080-A1 | Method for detecting cytosine methylations | QIAGEN GMBH (DE) | 2004-08-05 | — | — | US | disclosed |