Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.48 |
| ▸ | F10 | P00742 | 8/20 | 0.46 |
| ▸ | CETP | P11597 | 4/20 | 0.44 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.39 |
| ▸ | TNKS | O95271 | 1/20 | 0.38 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.38 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.38 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6189513 | 0.93 | F10 (0.53) | GPR119F10CETPALK | |
| SCHEMBL6735302 | 0.86 | GPR119 (0.48) | GPR119F10CETPALKCHEK2 | |
| SCHEMBL6188847 | 0.86 | GPR119 (0.53) | GPR119F10CETPALKCHEK2 | |
| SCHEMBL6189509 | 0.81 | F10 (0.49) | GPR119F10CETPALKCHEK2 | |
| SCHEMBL6187947 | 0.79 | F10 (0.62) | GPR119F10CETP | |
| SCHEMBL6191546 | 0.78 | F10 (0.50) | GPR119F10CETPALK | |
| SCHEMBL6190950 | 0.76 | GPR119 (0.56) | GPR119F10CETPALKCHEK2 | |
| SCHEMBL6188951 | 0.74 | GPR119 (0.51) | GPR119F10CETPALKCHEK2 | |
| SCHEMBL6954502 | 0.74 | GPR119 (0.61) | GPR119CETPALKCHEK2 | |
| SCHEMBL6190499 | 0.73 | GPR119 (0.49) | GPR119F10CETPALKCHEK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040006099-A1 | Amidine compounds | JAPAN TOBACCO INC. | 2004-01-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040006099-A1 | Amidine compounds | F2, SERPINC1, F12 | GPR119 2900/4885F10 16/4885CETP 2058/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.