SCHEMBL673537

SCHEMBL673537

O=C(CCN1CC1)OCCOC(=O)CCN1CC1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.44
SMN1; SMN2 Q16637 2/20 0.42
MAPT P10636 4/20 0.41
POLB P06746 1/20 0.41
TP53 P04637 1/20 0.40
DGKA P23743 1/20 0.40
L3MBTL1 Q9Y468 1/20 0.40
TSHR P16473 2/20 0.39
ADRA2A P08913 1/20 0.38
ADRA1A P35348 1/20 0.38
GLA P06280 1/20 0.38
TDP1 Q9NUW8 1/20 0.38
BLM P54132 1/20 0.37
SLC6A4 P31645 1/20 0.36
SLC6A3 Q01959 1/20 0.36
THRA P10827 1/20 0.36
THRB P10828 1/20 0.36
PAOX Q6QHF9 1/20 0.35
FNTA P49354 1/20 0.35
FNTB P49356 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL820593 0.91 THRB (0.40) ALDH1A1SMN1; SMN2MAPTPOLBTP53
SCHEMBL18154851 0.89 SMN1; SMN2 (0.39) ALDH1A1SMN1; SMN2MAPTPOLBTP53
SCHEMBL5421607 0.89 THRB (0.42) ALDH1A1SMN1; SMN2MAPTPOLBDGKA
SCHEMBL30917891 0.89 SMN1; SMN2 (0.39) ALDH1A1SMN1; SMN2MAPTPOLBTP53
Propionic Acid SCHEMBL8979209 0.88 ALDH1A1 (0.41) ALDH1A1SMN1; SMN2MAPTPOLBTP53
SCHEMBL419258 0.87 ALDH1A1 (0.46) ALDH1A1SMN1; SMN2MAPTTP53DGKA
SCHEMBL674334 0.87 ALDH1A1 (0.46) ALDH1A1SMN1; SMN2MAPTTP53DGKA
SCHEMBL13485578 0.87 TP53 (0.47) ALDH1A1SMN1; SMN2POLBTP53L3MBTL1
SCHEMBL24575293 0.86 SMN1; SMN2 (0.37) ALDH1A1SMN1; SMN2MAPTPOLBTP53
SCHEMBL11126642 0.85 ALDH1A1 (0.50) ALDH1A1SMN1; SMN2MAPTPOLBTP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 45 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3456746-B1 TERMINAL-MODIFIED CONJUGATED DIENE-BASED POLYMER, RUBBER COMPOSITION, AND RUBBER ARTICLE BRIDGESTONE CORP (JP) 2023-04-19 EP disclosed
WO-2022124058-A1 POLYMER-METAL COMPLEX, TIRE, AND POLYMER ARTICLE 株式会社ブリヂストン 2022-06-16 WO disclosed
EP-3851489-A1 MODIFIED MULTI-COMPONENT COPOLYMER, RUBBER COMPOSITION, RESIN COMPOSITION, TIRE AND RESIN PRODUCT BRIDGESTONE CORPORATION (JP) 2021-07-21 EP disclosed
US-10875937-B2 Terminal-modified conjugated diene polymer, rubber composition and rubber article BRIDGESTONE CORPORATION (JP) 2020-12-29 US disclosed
US-20190161571-A1 TERMINAL-MODIFIED CONJUGATED DIENE POLYMER, RUBBER COMPOSITION, RUBBER PRODUCT AND METHOD FOR MANUFACTURING TERMINAL-MODIFIED CONJUGATED DIENE POLYMER BRIDGESTONE CORPORATION (JP) 2019-05-30 US disclosed
US-20190153123-A1 TERMINAL-MODIFIED CONJUGATED DIENE POLYMER, RUBBER COMPOSITION AND RUBBER ARTICLE BRIDGESTONE CORPORATION (JP) 2019-05-23 US disclosed
EP-3466985-A1 TERMINALLY MODIFIED CONJUGATED DIENE POLYMER, RUBBER COMPOSITION, RUBBER PRODUCT, AND METHOD FOR PRODUCING TERMINALLY MODIFIED CONJUGATED DIENE POLYMER Bridgestone Corporation (JP) 2019-04-10 EP disclosed
EP-3456746-A1 TERMINAL-MODIFIED CONJUGATED DIENE-BASED POLYMER, RUBBER COMPOSITION, AND RUBBER ARTICLE Bridgestone Corporation (JP) 2019-03-20 EP disclosed
US-10131722-B2 Method for preparing terminal-modified conjugated diene polymer, terminal-modified conjugated diene polymer, rubber composition and tire BRIDGESTONE CORPORATION (JP) 2018-11-20 US disclosed
US-20170275400-A1 METHOD FOR PREPARING TERMINAL-MODIFIED CONJUGATED DIENE POLYMER, TERMINAL-MODIFIED CONJUGATED DIENE POLYMER, RUBBER COMPOSITION AND TIRE BRIDGESTONE CORPORATION (JP) 2017-09-28 US disclosed
EP-0718366-B1 Polyester resin composition NIPPON CATALYTIC CHEM IND (JP) 2002-09-11 EP disclosed
US-20020006973-A1 Biodegradable recycled polyester resin and production process therefor NIPPON SHOKUBAI CO., LTD. 2002-01-17 US disclosed
EP-1160269-A2 Biodegradable recycled polyester resin and production process therefor Nippon Shokubai Co., Ltd. (JP) 2001-12-05 EP disclosed
EP-1148074-A2 Process for producing aliphatic polyester NIPPON SHOKUBAI CO., LTD. (JP) 2001-10-24 EP disclosed
EP-0710684-B1 Preparation process of polyhydroxycarboxylic acid MITSUI CHEMICALS INC (JP) 2001-01-31 EP disclosed
US-5843573-A Polyester resin composition NIPPON SHOKUBAI CO., LTD. (JP) 1998-12-01 US disclosed
US-5770683-A Preparation process of polyhydroxycarboxylic acid MITSUI TOATSU CHEMICALS, INC. (JP) 1998-06-23 US disclosed
US-5616681-A CARRYING OUT RING-OPENING POLYMERIZATION OF CYCLIC ACID ANHYDRIDE WITH CYCLIC ETHER IN PRESENCE OF ZIRCONIUM COMPOUND NIPPON SHOKUBAI CO., LTD. (JP) 1997-04-01 US disclosed
EP-0718366-A2 Polyester resin composition NIPPON SHOKUBAI CO., LTD. (JP) 1996-06-26 EP disclosed
EP-0710685-A2 Process for producing aliphatic polyester NIPPON SHOKUBAI CO., LTD. (JP) 1996-05-08 EP disclosed