Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | TSHR | P16473 | 3/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | CASP1 | P29466 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.42 |
| ▸ | AKR1C1 | Q04828 | 2/20 | 0.42 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.42 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 3/20 | 0.40 |
| ▸ | DPP4 | P27487 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11049300 | 0.88 | CYP3A4 (0.45) | ALDH1A1TSHRTP53CASP1SMN1; SMN2 | |
| SCHEMBL543424 | 0.86 | CYP3A4 (0.45) | ALDH1A1TSHRTP53CASP1SMN1; SMN2 | |
| SCHEMBL3136996 | 0.86 | TSHR (0.43) | ALDH1A1TSHRTP53CASP1SMN1; SMN2 | |
| SCHEMBL11727816 | 0.85 | DPP4 (0.46) | ALDH1A1TSHRTP53CASP1SMN1; SMN2 | |
| SCHEMBL7738805 | 0.84 | ALDH1A1 (0.45) | ALDH1A1TSHRTP53CASP1SMN1; SMN2 | |
| SCHEMBL705877 | 0.84 | DPP4 (0.35) | ALDH1A1TSHRTP53CASP1SMN1; SMN2 | |
| SCHEMBL5465587 | 0.82 | CYP3A4 (0.45) | ALDH1A1TSHRTP53CASP1SMN1; SMN2 | |
| SCHEMBL31194455 | 0.82 | CYP3A4 (0.45) | ALDH1A1TSHRTP53CASP1SMN1; SMN2 | |
| SCHEMBL11680098 | 0.81 | TSHR (0.39) | ALDH1A1TSHRTP53CASP1SMN1; SMN2 | |
| SCHEMBL11343587 | 0.81 | ALDH1A1 (0.40) | ALDH1A1TSHRTP53CASP1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116589475-B | Preparation method of 2',4',5',7' -tetrachloro-5 (6) -carboxyl-4, 7-dichloro fluorescein | 北京欧凯纳斯生化科技有限公司 | 2023-09-29 | — | — | CN | claimed |
| CN-116589475-A | Preparation method of 2',4',5',7' -tetrachloro-5 (6) -carboxyl-4, 7-dichloro fluorescein | 北京欧凯纳斯生化科技有限公司 | 2023-08-15 | — | — | CN | claimed |
| CN-114736213-B | Preparation method of carboxyl-tetrachloro-fluorescein | 合肥华纳生物医药科技有限公司 | 2024-02-02 | — | — | CN | disclosed |
| CN-116589475-B | Preparation method of 2',4',5',7' -tetrachloro-5 (6) -carboxyl-4, 7-dichloro fluorescein | 北京欧凯纳斯生化科技有限公司 | 2023-09-29 | — | — | CN | disclosed |
| CN-116589475-B | Preparation method of 2',4',5',7' -tetrachloro-5 (6) -carboxyl-4, 7-dichloro fluorescein | 北京欧凯纳斯生化科技有限公司 | 2023-09-29 | — | — | CN | disclosed |
| CN-116589475-A | Preparation method of 2',4',5',7' -tetrachloro-5 (6) -carboxyl-4, 7-dichloro fluorescein | 北京欧凯纳斯生化科技有限公司 | 2023-08-15 | — | — | CN | disclosed |
| CN-116589475-A | Preparation method of 2',4',5',7' -tetrachloro-5 (6) -carboxyl-4, 7-dichloro fluorescein | 北京欧凯纳斯生化科技有限公司 | 2023-08-15 | — | — | CN | disclosed |
| CN-114736213-A | Preparation method of carboxyl-tetrachloro-fluorescein | 合肥华纳生物医药科技有限公司 | 2022-07-12 | — | — | CN | disclosed |
| US-6673550-B2 | PROBES FOR USE IN THE DETECTION AND MEASUREMENT OF PREFERENTIAL COMPOUND IN SAMPLE | ACLARA BIOSCIENCES, INC. | 2004-01-06 | — | — | US | disclosed |
| US-20020146726-A1 | Electrophoretic tag reagents comprising fluorescent compounds | ACLARA BIOSCIENCES, INC. | 2002-10-10 | — | — | US | disclosed |
| US-20020142329-A1 | Compositions and methods employing cleavable electrophoretic tag reagents | ACLARA BIOSCIENCES, INC. | 2002-10-03 | — | — | US | disclosed |
| EP-0500779-A4 | — | — | 1994-02-23 | — | — | EP | disclosed |
| EP-0500779-A1 | 4,7-DICHLOROFLUORESCEIN DYES AS MOLECULAR PROBES | THE PERKIN-ELMER CORPORATION (US) | 1992-09-02 | — | — | EP | disclosed |
| WO-1991007507-A1 | 4,7-DICHLOROFLUORESCEIN DYES AS MOLECULAR PROBES | APPLIED BIOSYSTEMS, INC. (US) | 1991-05-30 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020142329-A1 | Compositions and methods employing cleavable electrophoretic tag reagents | ENDOD1, TMPRSS15, ECE1 | ALDH1A1 3314/4885TSHR 1470/4885TP53 1732/4885 |
| US-20020146726-A1 | Electrophoretic tag reagents comprising fluorescent compounds | ENDOD1, ECE1, ELANE | ALDH1A1 2656/4885TSHR 1339/4885TP53 623/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.