Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
| ▸ | PPOX | P50336 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | GPR174 | Q9BXC1 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6725089 | 0.79 | TDP1 (0.37) | MAPTTDP1ALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL6727422 | 0.79 | ALDH1A1 (0.35) | MAPTTDP1ALDH1A1CYP1A2CYP2C9 | |
| SCHEMBL7014437 | 0.78 | CYP1A2 (0.39) | MAPTPPOXALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL6727669 | 0.78 | MAPK1 (0.38) | MAPTALDH1A1POLB | |
| SCHEMBL6724660 | 0.77 | ALDH1A1 (0.35) | MAPTTDP1ALDH1A1CYP1A2CYP2C9 | |
| SCHEMBL10619803 | 0.73 | MAPT (0.39) | MAPTPPOXALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL12065746 | 0.73 | MAPT (0.49) | MAPTRXFP1PPOXTDP1ALDH1A1 | |
| SCHEMBL9863069 | 0.73 | MAPT (0.50) | MAPTTDP1ALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL10362441 | 0.72 | ALDH1A1 (0.41) | MAPTPPOXTDP1ALDH1A1SMN1; SMN2 | |
| SCHEMBL6732678 | 0.71 | P2RX3 (0.40) | MAPTALDH1A1CYP1A2CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040063580-A1 | Bicyclic triazolone derivatives and a herbicides containing the same | SUMITOMO CHEMICAL TAKEDA AGRO COMPANY, LIMITED (JP) | 2004-04-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040063580-A1 | Bicyclic triazolone derivatives and a herbicides containing the same | WEE1, WEE2, BAK1 | MAPT 4198/4885RXFP1 1251/4885PPOX 3599/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.