SCHEMBL673560

SCHEMBL673560

C[C](C1CCCCC1)C1CCCCC1

nearest known ligand 0.47

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
CES2 O00748 1/20 0.47
CES1 P23141 1/20 0.47
MGLL Q99685 1/20 0.41
HDAC8 Q9BY41 1/20 0.39
HDAC6 Q9UBN7 1/20 0.39
NOS2 P35228 1/20 0.38
CTSK P43235 1/20 0.38
TSHR P16473 3/20 0.38
ALDH1A1 P00352 1/20 0.38
RECQL P46063 1/20 0.37
LMNA P02545 2/20 0.34
MEN1 O00255 1/20 0.34
KMT2A Q03164 1/20 0.34
HSD11B1 P28845 3/20 0.33
GAA P10253 2/20 0.33
PKM P14618 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
HSD11B2 P80365 1/20 0.32
EPHX1 P07099 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3870753 1.00 CES2 (0.47) CES2CES1MGLLHDAC8HDAC6
SCHEMBL6265136 1.00 CES2 (0.47) CES2CES1MGLLHDAC8HDAC6
SCHEMBL1858120 1.00 CES2 (0.47) CES2CES1MGLLHDAC8HDAC6
SCHEMBL17801457 0.97 CES2 (0.45) CES2CES1MGLLHDAC8HDAC6
SCHEMBL3881584 0.96 CES2 (0.42) CES2CES1MGLLHDAC8HDAC6
SCHEMBL6272207 0.93 CES2 (0.40) CES2CES1MGLLHDAC8HDAC6
SCHEMBL9830137 0.93 CES2 (0.40) CES2CES1MGLLHDAC8HDAC6
SCHEMBL7827736 0.89 NOS2 (0.40) CES2CES1MGLLNOS2CTSK
SCHEMBL985067 0.86
SCHEMBL4203062 0.81

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 100 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11681222-B2 Fluorine-containing polymer, purification method, and radiation-sensitive resin composition JSR CORPORATION (JP) 2023-06-20 US disclosed
US-20220137508-A9 FLUORINE-CONTAINING POLYMER, PURIFICATION METHOD, AND RADIATION-SENSITIVE RESIN COMPOSITION JSR CORPORATION (JP) 2022-05-05 US disclosed
US-20210278764-A1 FLUORINE-CONTAINING POLYMER, PURIFICATION METHOD, AND RADIATION-SENSITIVE RESIN COMPOSITION JSR CORPORATION (JP) 2021-09-09 US disclosed
US-11036133-B2 Fluorine-containing polymer, purification method, and radiation-sensitive resin composition JSR CORPORATION (JP) 2021-06-15 US disclosed
US-20200124961-A1 FLUORINE-CONTAINING POLYMER, PURIFICATION METHOD, AND RADIATION-SENSITIVE RESIN COMPOSITION JSR CORPORATION (JP) 2020-04-23 US disclosed
US-10620534-B2 Fluorine-containing polymer, purification method, and radiation-sensitive resin composition JSR CORPORATION (JP) 2020-04-14 US disclosed
US-20190278175-A9 FLUORINE-CONTAINING POLYMER, PURIFICATION METHOD, AND RADIATION-SENSITIVE RESIN COMPOSITION JSR CORPORATION (JP) 2019-09-12 US disclosed
US-20190025695-A1 FLUORINE-CONTAINING POLYMER, PURIFICATION METHOD, AND RADIATION-SENSITIVE RESIN COMPOSITION JSR CORPORATION (JP) 2019-01-24 US disclosed
US-10082733-B2 Fluorine-containing polymer, purification method, and radiation-sensitive resin composition JSR CORPORATION (JP) 2018-09-25 US disclosed
EP-2325694-B1 RADIATION-SENSITIVE RESIN COMPOSITION, AND RESIST PATTERN FORMATION METHOD JSR CORP (JP) 2017-11-08 EP disclosed
EP-0846108-A1 AMINO-SUBSTITUTED THIADIAZOLES, PYRIMIDINES, TRIAZINES OR TRIAZOLES USEFUL AS CTF RECEPTOR ANTAGONISTS NEUROCRINE BIOSCIENCES, INC. (US) 1998-06-10 EP disclosed
WO-1998019693-A1 COMBINATORIAL LIBRARIES OF CYCLIC UREA AND CYCLIC THIOUREA DERIVATIVES AND COMPOUNDS THEREIN TREGA BIOSCIENCES, INC. (US) 1998-05-14 WO disclosed
WO-1996039400-A1 AMINO-SUBSTITUTED THIADIAZOLES, PYRIMIDINES, TRIAZINES OR TRIAZOLES USEFUL AS CTF RECEPTOR ANTAGONISTS NEUROCRINE BIOSCIENCES, INC. (US) 1996-12-12 WO disclosed
US-5491132-A HYPOTENSIVE AGENT FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1996-02-13 US disclosed
CN-1030922-C Process for preparing amino acid derivatives FUJISAWA PHARMACEUTICAL CO (JP) 1996-02-07 CN disclosed
CN-1063691-A Amino acid derivatives and preparation method thereof and medicinal compositions FUJISAWA PHARMACEUTICAL CO (JP) 1992-08-19 CN disclosed
EP-0476515-A1 New amino acid derivatives, a process for the preparation thereof and pharmaceutical composition comprising the same FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1992-03-25 EP disclosed
CN-1055567-A Textile treatment ALBRIGHT & WILSON (GB) 1991-10-23 CN disclosed
EP-0275436-B1 PROCESS FOR PREPARING TERT.-AMYLBENZOYLBENZOIC ACID BASF Aktiengesellschaft (DE) 1990-06-27 EP disclosed
EP-0275436-A1 Process for preparing tert.-amylbenzoylbenzoic acid BASF Aktiengesellschaft (DE) 1988-07-27 EP disclosed