SCHEMBL673604

SCHEMBL673604

CO[PH](=O)OCc1ccccc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.44
ALDH1A1 P00352 5/20 0.44
IDO1 P14902 1/20 0.41
AGXT P21549 1/20 0.40
CA1 P00915 1/20 0.39
CA2 P00918 1/20 0.39
CA9 Q16790 1/20 0.39
MAOB P27338 4/20 0.39
LMNA P02545 2/20 0.39
KDM4E B2RXH2 1/20 0.39
L3MBTL1 Q9Y468 3/20 0.38
MAPK1 P28482 2/20 0.38
TDP1 Q9NUW8 2/20 0.38
MAPT P10636 2/20 0.38
MAOA P21397 2/20 0.38
RAB9A P51151 2/20 0.38
SMN1; SMN2 Q16637 2/20 0.38
SLC6A2 P23975 1/20 0.38
SLC6A3 Q01959 1/20 0.38
KMT2A Q03164 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL36370 0.87 TSHR (0.52) TSHRALDH1A1IDO1AGXTCA1
SCHEMBL29806030 0.87 TSHR (0.52) TSHRALDH1A1IDO1AGXTCA1
Butane SCHEMBL9066594 0.83 TSHR (0.44) TSHRALDH1A1IDO1AGXTCA1
SCHEMBL6054451 0.82 TSHR (0.43) TSHRALDH1A1IDO1AGXTCA1
SCHEMBL8038501 0.80 IDO1 (0.45) ALDH1A1IDO1CA1CA2CA9
SCHEMBL9818255 0.79 TSHR (0.44) TSHRALDH1A1IDO1AGXTCA1
SCHEMBL1162720 0.79 TSHR (0.44) TSHRALDH1A1IDO1AGXTCA1
SCHEMBL6213154 0.79 IDO1 (0.52) TSHRALDH1A1IDO1AGXTCA1
SCHEMBL27545548 0.79 TSHR (0.44) TSHRALDH1A1IDO1AGXTCA1
SCHEMBL7054240 0.78 TSHR (0.48) TSHRALDH1A1IDO1AGXTCA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 63 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230130333-A1 METHOD FOR MANUFACTURING PHOSPHONATE ESTERS AND METHOD FOR MANUFACTURING PHOSPHATE ESTERS FUJIFILM WAKO PURE CHEMICAL CORPORATION (JP) 2023-04-27 US disclosed
EP-4116310-A1 METHOD FOR MANUFACTURING PHOSPHONATE ESTERS AND METHOD FOR MANUFACTURING PHOSPHATE ESTERS FUJIFILM Wako Pure Chemical Corporation (JP) 2023-01-11 EP disclosed
CN-107592895-B Method of pumping an aqueous fluid containing a surface modifying treatment agent into a well 通用电气(GE)贝克休斯有限责任公司 2020-12-25 CN disclosed
CN-105339376-B Electrochromic compounds, electrochromic compositions, display element and Light modulating device 株式会社理光 2017-08-08 CN disclosed
US-20120252979-A1 Process for Producing Blends of Syndiotactic, 1,2-Polybutadiene and Rubbery Elastomers RADEMACHER CHRISTINE (US) 2012-10-04 US disclosed
US-8067503-B2 Process for producing blends of syndiotactic, 1,2-polybutadiene and rubbery elastomers BRIDGESTONE CORPORATION (JP) 2011-11-29 US disclosed
EP-1476480-B1 POLYMERIZATION PROCESS FOR PREPARING SYNDIOTACTIC 1,2-POLYBUTADIENE BRIDGESTONE CORP (JP) 2009-07-22 EP disclosed
EP-0994128-B1 Process and iron-based catalyst composition for the production of syndiotactic 1,2-polybutadiene BRIDGESTONE CORP (JP) 2007-08-01 EP disclosed
US-20070161748-A1 PROCESS FOR PRODUCING BLENDS OF SYNDIOTACTIC, 1,2-POLYBUTADIENE AND RUBBERY ELASTOMERS BRIDGESTONE CORPORATION 2007-07-12 US disclosed
US-20040242780-A1 using a catalyst that is based on a chromium-containing compound, a hydrogen phosphite, and an organomagnesium compound, or a catalyst based on a molybdenum or iron-compound, a hydrogen phosphite and organoaluminum compound; tire sidewalls; obviates the need for high-temperature mixing BRIDGESTONE CORPORATION (JP) 2004-12-02 US disclosed
US-6197888-B1 FORMED BY COMBINING AN IRON-CONTAINING COMPOUND, A HYDROGEN PHOSPHITE, AND AN ORGANOALUMINUM COMPOUND. BRIDGESTONE CORPORATION (JP) 2001-03-06 US disclosed
CN-1060480-C Substituted phenoxyl acetyloxy hydrocarbyl phosphonate with phytocidal activity and its preparation UNIV HUAZHONG (CN) 2001-01-10 CN disclosed
WO-2000075201-A1 MOLYBDENUM-BASED CATALYST COMPOSITION FOR POLYMERIZING CONJUGATED DIENES BRIDGESTONE CORPORATION (JP) 2000-12-14 WO disclosed
EP-0994127-A1 Method of preparing syndiotactic 1,2-polybutadiene with a chromium-based catalyst system Bridgestone Corporation (JP) 2000-04-19 EP disclosed
EP-0994129-A1 Iron-based catalyst composition and process for producing syndiotactic 1,2-polybutadiene Bridgestone Corporation (JP) 2000-04-19 EP disclosed
EP-0994128-A1 Process and iron-based catalyst composition for the production of syndiotactic 1,2-polybutadiene Bridgestone Corporation (JP) 2000-04-19 EP disclosed
US-5919875-A ORGANOALUMINUM HYDRIDE, ORGANIC HYDROGEN PHOSPHITE BRIDGESTONE CORPORATION (JP) 1999-07-06 US disclosed
EP-0926167-A1 Preparation of syndiotactic 1,2-polybutadiene using a chromium-containing catalyst system Bridgestone Corporation (JP) 1999-06-30 EP disclosed
CN-1197800-A Substituted phenoxyl acetyloxy hydrocarbyl phosphonate with phytocidal activity and its preparation UNIV HUAZHONG (CN) 1998-11-04 CN disclosed
US-4318783-A Process for the preparation of optionally substituted benzaldehyde dialkyl acetals BAYER AKTIENGESELLSCHAFT (DE) 1982-03-09 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230130333-A1 METHOD FOR MANUFACTURING PHOSPHONATE ESTERS AND METHOD FOR MANUFACTURING PHOSPHATE ESTERS PHOSPHO1, PHYKPL, PIK3CA TSHR 2166/4885ALDH1A1 340/4885IDO1 4224/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.