Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 3/20 | 0.45 |
| ▸ | MAOB | P27338 | 6/20 | 0.41 |
| ▸ | APP | P05067 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.38 |
| ▸ | RXRA | P19793 | 1/20 | 0.38 |
| ▸ | RXRB | P28702 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA7 | P43166 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | MAOA | P21397 | 2/20 | 0.36 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2016123 | 0.88 | IDO1 (0.52) | IDO1MAOBAPPHTR2ATAAR1 | |
| SCHEMBL5051394 | 0.83 | IDO1 (0.44) | IDO1MAOBAPPHTR2ATAAR1 | |
| SCHEMBL673604 | 0.80 | TSHR (0.44) | IDO1MAOBKDM4EMAPTALDH1A1 | |
| SCHEMBL4938371 | 0.76 | IDO1 (0.48) | IDO1MAOBAPPHTR2ATAAR1 | |
| SCHEMBL7761382 | 0.75 | IDO1 (0.54) | IDO1MAOBMAPTALDH1A1KMT2A | |
| Butane SCHEMBL2802241 | 0.74 | POLB (0.42) | IDO1MAOBAPPRXRARXRB | |
| SCHEMBL7197241 | 0.72 | IDO1 (0.55) | IDO1MAOBAPPTAAR1ALDH1A1 | |
| SCHEMBL1995347 | 0.72 | IDO1 (0.58) | IDO1MAOBAPPHTR2ATAAR1 | |
| SCHEMBL9849327 | 0.71 | TRPA1 (0.39) | IDO1ALDH1A1CA2CA9 | |
| SCHEMBL5432093 | 0.71 | AGXT (0.52) | IDO1MAOBTAAR1MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6043341-A | PHOSPHONYLATING AGENTS FOR REGIOSELECTIVE AND REPRODUCIBLE CONVERSION OF PEPTIDES TO PHOSPHONIC ACID PRODRUGS | ELI LILLY & CO. (US) | 2000-03-28 | — | — | US | disclosed |
| EP-0906915-A1 | Preparation of cyclic peptide antifungal agents | ELI LILLY AND COMPANY (US) | 1999-04-07 | — | — | EP | disclosed |
| WO-1999006062-A1 | CYCLIC PEPTIDE ANTIFUNGAL AGENTS | ELI LILLY AND COMPANY (US) | 1999-02-11 | — | — | WO | disclosed |