Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | TNF | P01375 | 2/20 | 0.33 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27701295 | 0.86 | RAB9A (0.35) | TSHRKMT2AALDH1A1MAPTKAT2B | |
| SCHEMBL27701253 | 0.81 | TSHR (0.45) | TSHRLMNAPOLBKMT2AALDH1A1 | |
| SCHEMBL26097101 | 0.79 | TSHR (0.54) | TSHRLMNAPOLBKMT2AALDH1A1 | |
| SCHEMBL6737633 | 0.74 | HRH3 (0.41) | TSHRLMNAPOLBALDH1A1MAPT | |
| SCHEMBL6735212 | 0.72 | KAT2B (0.38) | KMT2ATNFKAT2B | |
| SCHEMBL4394520 | 0.71 | HRH3 (0.37) | KMT2AALDH1A1 | |
| SCHEMBL5032385 | 0.70 | TSHR (0.44) | TSHRLMNAPOLBKMT2AALDH1A1 | |
| Hydrochloric Acid SCHEMBL4123134 | 0.69 | TSHR (0.43) | TSHRLMNAPOLBKMT2AALDH1A1 | |
| SCHEMBL8168251 | 0.68 | TNF (0.49) | TSHRPOLBALDH1A1TNF | |
| SCHEMBL4385456 | 0.67 | TSHR (0.64) | TSHRLMNAPOLBKAT2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101041636-B | Method for synthesizing heterocyclic ketenes amine condensation derivatives | CHINESE ACAD INST CHEMISTRY | 2010-05-12 | — | — | CN | disclosed |
| CN-101041636-A | Method for synthesizing heterocyclic ketenes amine condensation derivatives | CHINESE ACAD INST CHEMISTRY (CN) | 2007-09-26 | — | — | CN | disclosed |
| US-20040127507-A1 | Imidazolidine compounds | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2004-07-01 | — | — | US | disclosed |
| US-20040122026-A1 | Imidazolidine compounds | MILLENNIUM PHARMACEUTICALS, INC. | 2004-06-24 | — | — | US | disclosed |
| US-20030225288-A1 | Imidazolidine compounds | MILLENNIUM PHARMACEUTICALS, INC. | 2003-12-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040127507-A1 | Imidazolidine compounds | IRAK1, IRAK4, IRAK2 | TSHR 2768/4885LMNA 4169/4885POLB 3185/4885 |
| US-20030225288-A1 | Imidazolidine compounds | IRAK1, IRAK4, IRAK2 | TSHR 2768/4885LMNA 4169/4885POLB 3185/4885 |
| US-20040122026-A1 | Imidazolidine compounds | IRAK1, IRAK4, IRAK2 | TSHR 2768/4885LMNA 4169/4885POLB 3185/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.