Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 2/20 | 0.56 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.56 |
| ▸ | MIF | P14174 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.44 |
| ▸ | ELANE | P08246 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | LNPEP | Q9UIQ6 | 1/20 | 0.43 |
| ▸ | MDM4 | O15151 | 1/20 | 0.43 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | KDR | P35968 | 1/20 | 0.40 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.40 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.40 |
| ▸ | MMP1 | P03956 | 1/20 | 0.40 |
| ▸ | MMP2 | P08253 | 1/20 | 0.40 |
| ▸ | MMP3 | P08254 | 1/20 | 0.40 |
| ▸ | MMP9 | P14780 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6737972 | 0.86 | PTGS2 (0.46) | ESR1ESR2MIFPTGS2SLC7A5 | |
| SCHEMBL6735869 | 0.85 | ESR1 (0.51) | ESR1ESR2MIFKMT2ANPSR1 | |
| SCHEMBL6738744 | 0.85 | ESR1 (0.43) | ESR1ESR2MIFTSHRSLC7A5 | |
| SCHEMBL6737968 | 0.84 | SLC7A5 (0.50) | ESR1ESR2SLC7A5 | |
| SCHEMBL542969 | 0.83 | ESR1 (0.63) | ESR1ESR2MIFKMT2ANPSR1 | |
| SCHEMBL5024580 | 0.83 | ESR1 (0.63) | ESR1ESR2MIFKMT2ANPSR1 | |
| SCHEMBL542970 | 0.83 | ESR1 (0.63) | ESR1ESR2MIFKMT2ANPSR1 | |
| SCHEMBL3993110 | 0.79 | ESR1 (0.58) | ESR1ESR2MIFKMT2ANPSR1 | |
| SCHEMBL3535227 | 0.79 | ESR1 (0.58) | ESR1ESR2MIFKMT2ANPSR1 | |
| SCHEMBL3535230 | 0.79 | ESR1 (0.58) | ESR1ESR2MIFKMT2ANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040248849-A1 | 3-Aryl-A-oxy substituted propanoic acids and a process for their preparation | DR. REDDY'S LABORATORIES INC. | 2004-12-09 | — | — | US | claimed |
| WO-2003002575-A1 | 3-ARYL-$G(a)-OXY SUBSTITUTED PROPANOIC ACIDS AND A PROCESS FOR THEIR PREPARATION | DR. REDDY'S LABORATORIES LTD. (IN) | 2003-01-09 | — | — | WO | claimed |
| US-20040248849-A1 | 3-Aryl-A-oxy substituted propanoic acids and a process for their preparation | DR. REDDY'S LABORATORIES INC. | 2004-12-09 | — | — | US | disclosed |
| WO-2003002575-A1 | 3-ARYL-$G(a)-OXY SUBSTITUTED PROPANOIC ACIDS AND A PROCESS FOR THEIR PREPARATION | DR. REDDY'S LABORATORIES LTD. (IN) | 2003-01-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040248849-A1 | 3-Aryl-A-oxy substituted propanoic acids and a process for their preparation | GPR119, GLP1R, SLC5A1 | ESR1 3084/4885ESR2 1585/4885MIF 2010/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.