Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 5/20 | 0.40 |
| ▸ | CA4 | P22748 | 5/20 | 0.40 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.32 |
| ▸ | ACLY | P53396 | 1/20 | 0.32 |
| ▸ | KDM1A | O60341 | 2/20 | 0.31 |
| ▸ | KDM1B | Q8NB78 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 4/20 | 0.31 |
| ▸ | CA6 | P23280 | 4/20 | 0.31 |
| ▸ | MEP1B | Q16820 | 1/20 | 0.30 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.30 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.30 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22883762 | 0.81 | TDP1 (0.36) | CA2CA4TUBB1PDGFRBPDGFRA | |
| SCHEMBL31248689 | 0.79 | CA2 (0.38) | CA2CA4 | |
| SCHEMBL6739577 | 0.77 | TUBB1 (0.35) | TUBB1PDGFRBPDGFRA | |
| SCHEMBL5208683 | 0.76 | CA2 (0.41) | CA2CA4TUBB1ACLYCA1 | |
| SCHEMBL31523571 | 0.75 | CA2 (0.34) | CA2CA4 | |
| SCHEMBL27929289 | 0.74 | HSD17B10 (0.49) | TUBB1MEP1BPTPN1 | |
| SCHEMBL12093633 | 0.73 | CYP19A1 (0.36) | TUBB1ACLYPDGFRBPDGFRA | |
| SCHEMBL29387130 | 0.72 | KDM1A (0.37) | CA2CA4KDM1AKDM1BCA1 | |
| SCHEMBL27628234 | 0.72 | CA2 (0.39) | CA2CA4TUBB1ACLYCA1 | |
| SCHEMBL28031715 | 0.72 | SOS1 (0.42) | CA2TUBB1CA1MEP1BPTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6683218-B1 | REACTING AN ARYL FLUORIDE WITH HALOGENATED HYDROCARBON AND MAGNESIUM; METALLIZATION, BORATING; DISTILLING OUT DIETHYL ETHER OR TETRAHYDROFURAN SOLVENT | NIPPON SHOKUBAI CO., LTD. (JP) | 2004-01-27 | — | — | US | disclosed |
| EP-0825195-B1 | PRODUCING PROCESS OF FLUOROARYL MAGNESIUM DERIVATIVE AND PRODUCING PROCESS OF (FLUOROARYL)BORANE COMPOUND | NIPPON CATALYTIC CHEM IND (JP) | 2003-11-12 | — | — | EP | disclosed |
| US-6057480-A | Process for preparing fluoroaryl magnesium derivative and process for preparing (fluoroaryl) borane compound | NIPPON SHOKUBAI CO., LTD. (JP) | 2000-05-02 | — | — | US | disclosed |
| EP-0838466-A2 | Producing process of (fluoroaryl) borane compound and producing process of tetrakis (fluoroaryl) borate derivative | NIPPON SHOKUBAI CO., LTD. (JP) | 1998-04-29 | — | — | EP | disclosed |
| EP-0825195-A1 | PROCESS FOR THE PREPARATION OF FLUORINATED ARYLMAGNESIUM DERIVATIVES AND PROCESS FOR THE PREPARATION OF (FLUORINATED ARYL)BORON COMPOUNDS | NIPPON SHOKUBAI CO., LTD. (JP) | 1998-02-25 | — | — | EP | disclosed |