Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | LCK | P06239 | 1/20 | 0.43 |
| ▸ | FYN | P06241 | 1/20 | 0.43 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.41 |
| ▸ | TPMT | P51580 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | MEP1B | Q16820 | 1/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.36 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.36 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27486423 | 0.86 | HSD17B10 (0.49) | HSD17B10LCKFYNGPR35TPMT | |
| SCHEMBL28031715 | 0.85 | SOS1 (0.42) | HSD17B10ALDH1A1HPGDKDM4EMEP1B | |
| SCHEMBL6422815 | 0.84 | HSD17B10 (0.44) | HSD17B10LCKFYNTPMTALDH1A1 | |
| SCHEMBL7010260 | 0.83 | HSD17B10 (0.49) | HSD17B10LCKFYNGPR35TPMT | |
| SCHEMBL25256255 | 0.81 | HSD17B10 (0.54) | HSD17B10LCKFYNGPR35TPMT | |
| SCHEMBL28583415 | 0.81 | MEN1 (0.42) | HSD17B10LCKFYNALDH1A1KDM4E | |
| SCHEMBL28424948 | 0.80 | HSD17B10 (0.44) | HSD17B10LCKFYNTPMTALDH1A1 | |
| SCHEMBL20551451 | 0.79 | ALDH1A1 (0.41) | HSD17B10LCKFYNTPMTALDH1A1 | |
| SCHEMBL27875674 | 0.79 | HSD17B10 (0.41) | HSD17B10LCKFYNTPMTALDH1A1 | |
| SCHEMBL27540803 | 0.78 | HSD17B10 (0.50) | HSD17B10LCKFYNGPR35TPMT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103467294-B | The preparation method of a kind of 3-bromo-4-difluoro-methoxy-benzoic acid methyl esters | SHANGHAI INSTITUTE OF PHARMACEUTICAL INDUSTRY (CN) | 2015-09-23 | — | — | CN | claimed |
| CN-103467294-A | 3-bromo-4-difluoromethoxy methyl benzoate preparation method | SHANGHAI INST PHARM INDUSTRY | 2013-12-25 | — | — | CN | claimed |
| CN-103467294-A | 3-bromo-4-difluoromethoxy methyl benzoate preparation method | SHANGHAI INST PHARM INDUSTRY | 2013-12-25 | — | — | CN | disclosed |