Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.71 |
| ▸ | POLB | P06746 | 2/20 | 0.71 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.71 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.62 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.62 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.62 |
| ▸ | MEN1 | O00255 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.57 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.57 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.56 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 3/20 | 0.55 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.54 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17095630 | 0.98 | POLB (0.73) | ALDH1A1POLBKDM4ESMN1; SMN2L3MBTL1 | |
| SCHEMBL16054847 | 0.86 | L3MBTL1 (0.61) | ALDH1A1POLBKDM4ESMN1; SMN2L3MBTL1 | |
| SCHEMBL27087824 | 0.86 | ALDH1A1 (0.68) | ALDH1A1POLBKDM4ESMN1; SMN2L3MBTL1 | |
| SCHEMBL15156640 | 0.82 | L3MBTL1 (0.57) | ALDH1A1POLBKDM4EL3MBTL1TDP1 | |
| SCHEMBL6729837 | 0.82 | L3MBTL1 (0.64) | ALDH1A1POLBKDM4ESMN1; SMN2L3MBTL1 | |
| SCHEMBL1924050 | 0.82 | ALDH1A1 (0.62) | ALDH1A1POLBKDM4ESMN1; SMN2L3MBTL1 | |
| SCHEMBL4158661 | 0.82 | L3MBTL1 (0.57) | ALDH1A1POLBKDM4EL3MBTL1TDP1 | |
| SCHEMBL21383091 | 0.81 | L3MBTL1 (0.63) | ALDH1A1POLBKDM4ESMN1; SMN2L3MBTL1 | |
| SCHEMBL5238051 | 0.80 | L3MBTL1 (0.55) | ALDH1A1POLBKDM4ESMN1; SMN2L3MBTL1 | |
| SCHEMBL14238269 | 0.79 | L3MBTL1 (0.60) | ALDH1A1POLBKDM4ESMN1; SMN2L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040127507-A1 | Imidazolidine compounds | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2004-07-01 | — | — | US | disclosed |
| US-20040122026-A1 | Imidazolidine compounds | MILLENNIUM PHARMACEUTICALS, INC. | 2004-06-24 | — | — | US | disclosed |
| US-20030225288-A1 | Imidazolidine compounds | MILLENNIUM PHARMACEUTICALS, INC. | 2003-12-04 | — | — | US | disclosed |
| WO-2003087063-A1 | IMIDAZOLIDINE COMPOUNDS AS CHEMOKINE RECEPTOR MODULATORS | KYOWA HAKKO KOGYO CO., LTD. (JP) | 2003-10-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040127507-A1 | Imidazolidine compounds | IRAK1, IRAK4, IRAK2 | ALDH1A1 569/4885POLB 3185/4885KDM4E 4423/4885 |
| US-20030225288-A1 | Imidazolidine compounds | IRAK1, IRAK4, IRAK2 | ALDH1A1 569/4885POLB 3185/4885KDM4E 4423/4885 |
| US-20040122026-A1 | Imidazolidine compounds | IRAK1, IRAK4, IRAK2 | ALDH1A1 569/4885POLB 3185/4885KDM4E 4423/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.