Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.45 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.44 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | CETP | P11597 | 1/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4266412 | 0.81 | KCNK3 (0.61) | RAB9AGAAHTTSMN1; SMN2RXFP1 | |
| SCHEMBL1601556 | 0.79 | RAB9A (0.56) | RAB9AHTTSMN1; SMN2HPGDALDH1A1 | |
| SCHEMBL6282431 | 0.77 | HPGD (0.51) | RAB9AGAASMN1; SMN2KCNK3KCNK9 | |
| SCHEMBL161742 | 0.77 | L3MBTL1 (0.55) | RAB9AHTTSMN1; SMN2HPGDALDH1A1 | |
| SCHEMBL693444 | 0.76 | HPGD (0.66) | GAASMN1; SMN2KCNK3KCNK9HPGD | |
| SCHEMBL5847210 | 0.75 | HDAC3 (0.38) | RAB9AGAAHTTSMN1; SMN2RXFP1 | |
| SCHEMBL5847219 | 0.75 | HDAC3 (0.38) | RAB9AGAAHTTSMN1; SMN2RXFP1 | |
| SCHEMBL6757892 | 0.75 | HPGD (0.49) | RAB9AGAASMN1; SMN2KCNK3KCNK9 | |
| SCHEMBL20797095 | 0.74 | L3MBTL1 (0.51) | RAB9ASMN1; SMN2HPGDNPC1KDM4E | |
| SCHEMBL6615592 | 0.74 | HPGD (0.63) | GAAHTTSMN1; SMN2KCNK3KCNK9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6686484-B2 | ANTICOAGULANTS; SERINE PROTEASE INHIBITOR | PHARMACIA CORPORATION | 2004-02-03 | — | — | US | claimed |