SCHEMBL673790

SCHEMBL673790

O=[PH](OCC1CCCC1)OCC1CCCC1

nearest known ligand 0.41

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.36
SLC1A3 P43003 4/20 0.34
SLC1A2 P43004 4/20 0.34
SLC1A1 P43005 4/20 0.34
PARP15 Q460N3 3/20 0.32
PARP10 Q53GL7 3/20 0.32
CTSL P07711 1/20 0.32
CTSB P07858 1/20 0.32
CTSK P43235 1/20 0.32
ADH1B P00325 1/20 0.30
ADH1C P00326 1/20 0.30
ADH1A P07327 1/20 0.30
ADH4 P08319 1/20 0.30
ADH7 P40394 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL672855 0.97 LMNA (0.39) LMNASLC1A3SLC1A2SLC1A1PARP15
SCHEMBL672569 0.95 SLC1A3 (0.34) LMNASLC1A3SLC1A2SLC1A1PARP15
SCHEMBL672200 0.89 SLC1A3 (0.30) SLC1A3SLC1A2SLC1A1
SCHEMBL6063012 0.78 LMNA (0.37) LMNASLC1A3SLC1A2SLC1A1PARP15
SCHEMBL15263448 0.68 SLC1A3 (0.32) SLC1A3SLC1A2SLC1A1PARP15PARP10
SCHEMBL20531 0.67 CTSL (0.38) LMNASLC1A3SLC1A2SLC1A1PARP15
SCHEMBL1326091 0.67
SCHEMBL1703891 0.67
SCHEMBL23039739 0.65 CTSL (0.41) LMNASLC1A3SLC1A2SLC1A1CTSL
SCHEMBL16239892 0.65 CTSL (0.41) LMNASLC1A3SLC1A2SLC1A1CTSL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 54 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8067503-B2 Process for producing blends of syndiotactic, 1,2-polybutadiene and rubbery elastomers BRIDGESTONE CORPORATION (JP) 2011-11-29 US disclosed
EP-1476480-B1 POLYMERIZATION PROCESS FOR PREPARING SYNDIOTACTIC 1,2-POLYBUTADIENE BRIDGESTONE CORP (JP) 2009-07-22 EP disclosed
EP-0994128-B1 Process and iron-based catalyst composition for the production of syndiotactic 1,2-polybutadiene BRIDGESTONE CORP (JP) 2007-08-01 EP disclosed
US-20070161748-A1 PROCESS FOR PRODUCING BLENDS OF SYNDIOTACTIC, 1,2-POLYBUTADIENE AND RUBBERY ELASTOMERS BRIDGESTONE CORPORATION 2007-07-12 US disclosed
CN-1906143-A Method of deuteration using mixed catalyst WAKO PURE CHEM IND LTD (JP) 2007-01-31 CN disclosed
CN-1714060-A Method for deuteration or tritiation of heterocyclic ring WAKO PURE CHEM IND LTD (JP) 2005-12-28 CN disclosed
US-20040242780-A1 using a catalyst that is based on a chromium-containing compound, a hydrogen phosphite, and an organomagnesium compound, or a catalyst based on a molybdenum or iron-compound, a hydrogen phosphite and organoaluminum compound; tire sidewalls; obviates the need for high-temperature mixing BRIDGESTONE CORPORATION (JP) 2004-12-02 US disclosed
EP-1476480-A1 POLYMERIZATION PROCESS FOR PREPARING SYNDIOTACTIC 1,2-POLYBUTADIENE Bridgestone Corporation (JP) 2004-11-17 EP disclosed
US-6720397-B2 Using supersaturation solutiton and iron coordination catalyst BRIDGESTONE CORPORATION (JP) 2004-04-13 US disclosed
US-6620760-B2 Coordination catalyst BRIDGESTONE CORPORATION (JP) 2003-09-16 US disclosed
WO-2001034669-A1 IRON-BASED CATALYST COMPOSITION AND PROCESS FOR PRODUCING CONJUGATED DIENE POLYMERS BRIDGESTONE CORPORATION (JP) 2001-05-17 WO disclosed
WO-2001032724-A1 IRON-BASED CATALYST FOR PRODUCING OLIGOMERS OF CONJUGATED DIENES BRIDGESTONE CORPORATION (JP) 2001-05-10 WO disclosed
US-6201080-B1 CATALYTIC POLYMERIZATION OF BUTADIENE IN A SOLVENT BRIDGESTONE CORPORATION (JP) 2001-03-13 US disclosed
US-6197888-B1 FORMED BY COMBINING AN IRON-CONTAINING COMPOUND, A HYDROGEN PHOSPHITE, AND AN ORGANOALUMINUM COMPOUND. BRIDGESTONE CORPORATION (JP) 2001-03-06 US disclosed
WO-2000075201-A1 MOLYBDENUM-BASED CATALYST COMPOSITION FOR POLYMERIZING CONJUGATED DIENES BRIDGESTONE CORPORATION (JP) 2000-12-14 WO disclosed
EP-0994129-A1 Iron-based catalyst composition and process for producing syndiotactic 1,2-polybutadiene Bridgestone Corporation (JP) 2000-04-19 EP disclosed
EP-0994127-A1 Method of preparing syndiotactic 1,2-polybutadiene with a chromium-based catalyst system Bridgestone Corporation (JP) 2000-04-19 EP disclosed
EP-0994128-A1 Process and iron-based catalyst composition for the production of syndiotactic 1,2-polybutadiene Bridgestone Corporation (JP) 2000-04-19 EP disclosed
US-5919875-A ORGANOALUMINUM HYDRIDE, ORGANIC HYDROGEN PHOSPHITE BRIDGESTONE CORPORATION (JP) 1999-07-06 US disclosed
EP-0926167-A1 Preparation of syndiotactic 1,2-polybutadiene using a chromium-containing catalyst system Bridgestone Corporation (JP) 1999-06-30 EP disclosed