Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | GABRP | O00591 | 1/20 | 0.39 |
| ▸ | GABRD | O14764 | 1/20 | 0.39 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.39 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.39 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.39 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.39 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.39 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.39 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.39 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.39 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.39 |
| ▸ | GABRE | P78334 | 1/20 | 0.39 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.39 |
| ▸ | GABRG1 | Q8N1C3 | 1/20 | 0.39 |
| ▸ | GABRG3 | Q99928 | 1/20 | 0.39 |
| ▸ | GABRQ | Q9UN88 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6741469 | 0.90 | L3MBTL1 (0.43) | ALDH1A1L3MBTL1KMT2AMEN1ALOX15 | |
| SCHEMBL6738568 | 0.90 | ALDH1A1 (0.45) | ALDH1A1L3MBTL1GABRPGABRDGABRA1 | |
| SCHEMBL7460294 | 0.87 | ALDH1A1 (0.46) | ALDH1A1L3MBTL1KMT2AMEN1ALOX15 | |
| SCHEMBL7460302 | 0.87 | ALDH1A1 (0.46) | ALDH1A1L3MBTL1KMT2AMEN1ALOX15 | |
| SCHEMBL6738923 | 0.87 | ALDH1A1 (0.46) | ALDH1A1L3MBTL1KMT2AMEN1ALOX15 | |
| SCHEMBL6738927 | 0.87 | ALDH1A1 (0.46) | ALDH1A1L3MBTL1KMT2AMEN1ALOX15 | |
| SCHEMBL6740425 | 0.85 | ALDH1A1 (0.58) | ALDH1A1L3MBTL1KMT2AMEN1CYP3A4 | |
| SCHEMBL6742894 | 0.83 | ALDH1A1 (0.43) | ALDH1A1L3MBTL1GABRPGABRDGABRA1 | |
| SCHEMBL6734143 | 0.83 | ALDH1A1 (0.43) | ALDH1A1L3MBTL1GABRPGABRDGABRA1 | |
| SCHEMBL6733296 | 0.83 | ALDH1A1 (0.43) | ALDH1A1L3MBTL1GABRPGABRDGABRA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6686357-B1 | BENZIMIDAZOLO-PIPERIDINE COMPOUND | PFIZER, INC. | 2004-02-03 | — | — | US | disclosed |