SCHEMBL6738709

SCHEMBL6738709

OC1(C#CC#CC2(O)CCCC2)CCCC1

nearest known ligand 0.48

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.48
NPSR1 Q6W5P4 1/20 0.38
PAX8 Q06710 1/20 0.33
CTDSP1 Q9GZU7 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6740183 0.97 ALDH1A1 (0.52) ALDH1A1NPSR1PAX8CTDSP1
SCHEMBL947101 0.86 ALDH1A1 (0.53) ALDH1A1NPSR1PAX8CTDSP1
SCHEMBL9117075 0.75
SCHEMBL7943907 0.73 ALDH1A1 (0.48) ALDH1A1NPSR1PAX8CTDSP1
SCHEMBL4422406 0.73 ALDH1A1 (0.48) ALDH1A1NPSR1PAX8CTDSP1
SCHEMBL23085616 0.73 ALDH1A1 (0.48) ALDH1A1NPSR1PAX8CTDSP1
SCHEMBL11773747 0.73 ALDH1A1 (0.48) ALDH1A1NPSR1PAX8CTDSP1
SCHEMBL1966547 0.73 ALDH1A1 (0.48) ALDH1A1NPSR1PAX8CTDSP1
SCHEMBL6456132 0.73 ALDH1A1 (0.48) ALDH1A1NPSR1PAX8CTDSP1
SCHEMBL31261818 0.73 ALDH1A1 (0.48) ALDH1A1NPSR1PAX8CTDSP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6686428-B2 TRANSMETALLATION REAGENTS REACTED WITH ALPHA-HALOCARBONYL COMPOUNDS IN THE PRESENCE OF A METAL CATALYST THE PENN STATE RESEARCH FOUNDATION 2004-02-03 US disclosed
US-20020193543-A1 Transmetallation reagents reacted with alpha-halocarbonyl compounds in the presence of a metal catalyst NATIONAL INSTITUTES OF HEALTH 2002-12-19 US disclosed
US-6291061-B1 Hydrogen gettering packing material, and process for making same THE UNITED STATES OF AMERICA AS REPRESENTED BY THE UNITED STATES DEPARTMENT OF ENERGY 2001-09-18 US disclosed