SCHEMBL6740183

SCHEMBL6740183

OC1(C#CC#CC2(O)CCCCC2)CCCCC1

nearest known ligand 0.52

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.52
NPSR1 Q6W5P4 1/20 0.41
PAX8 Q06710 1/20 0.36
CTDSP1 Q9GZU7 1/20 0.33
HPGD P15428 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6738709 0.97 ALDH1A1 (0.48) ALDH1A1NPSR1PAX8CTDSP1
SCHEMBL947101 0.83 ALDH1A1 (0.53) ALDH1A1NPSR1PAX8CTDSP1HPGD
SCHEMBL6456132 0.77 ALDH1A1 (0.48) ALDH1A1NPSR1PAX8CTDSP1
SCHEMBL1966547 0.77 ALDH1A1 (0.48) ALDH1A1NPSR1PAX8CTDSP1
SCHEMBL31261818 0.77 ALDH1A1 (0.48) ALDH1A1NPSR1PAX8CTDSP1
SCHEMBL23085616 0.77 ALDH1A1 (0.48) ALDH1A1NPSR1PAX8CTDSP1
SCHEMBL4422406 0.77 ALDH1A1 (0.48) ALDH1A1NPSR1PAX8CTDSP1
SCHEMBL11773747 0.77 ALDH1A1 (0.48) ALDH1A1NPSR1PAX8CTDSP1
SCHEMBL7943907 0.77 ALDH1A1 (0.48) ALDH1A1NPSR1PAX8CTDSP1
SCHEMBL11774123 0.77 ALDH1A1 (0.48) ALDH1A1NPSR1PAX8CTDSP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9120935-B2 Hydrosilylation reaction inhibitors, and use thereof for preparing stable curable silicone compositions BLUESTAR SILICONES FRANCE SAS (FR) 2015-09-01 US claimed
US-20140329099-A1 HYDROSILYLATION REACTION INHIBITORS, AND USE THEREOF FOR PREPARING STABLE CURABLE SILICONE COMPOSITIONS BLUESTAR SILICONES FRANCE (FR) 2014-11-06 US claimed
US-4081468-A HERBICIDES STAUFFER CHEMICAL COMPANY (US) 1978-03-28 US claimed
US-20220380547-A1 THERMAL INTERFACE MATERIALS AND METHODS FOR APPLICATION HENKEL AG & CO. KGAA (DE) 2022-12-01 US disclosed
EP-4061907-A1 THERMAL INTERFACE MATERIALS AND METHODS FOR APPLICATION Henkel AG & Co. KGaA (DE) 2022-09-28 EP disclosed
US-9120935-B2 Hydrosilylation reaction inhibitors, and use thereof for preparing stable curable silicone compositions BLUESTAR SILICONES FRANCE SAS (FR) 2015-09-01 US disclosed
US-20140329099-A1 HYDROSILYLATION REACTION INHIBITORS, AND USE THEREOF FOR PREPARING STABLE CURABLE SILICONE COMPOSITIONS BLUESTAR SILICONES FRANCE (FR) 2014-11-06 US disclosed
EP-1189981-B1 USE OF AN INHIBITOR COMPOUND IN AN ORGANOSILICON COMPOSITION DOW CORNING SA (BE) 2004-10-27 EP disclosed
US-6686428-B2 TRANSMETALLATION REAGENTS REACTED WITH ALPHA-HALOCARBONYL COMPOUNDS IN THE PRESENCE OF A METAL CATALYST THE PENN STATE RESEARCH FOUNDATION 2004-02-03 US disclosed
US-6642184-B1 Sealing or plugging oil or gas wells by curing mixtures of polysiloxanes, curing agents, hydrosilation catalysts and crosslinking inhibitors, to form silicone gels or elastomers DOW CORNING S.A. (BE) 2003-11-04 US disclosed
US-20020193543-A1 Transmetallation reagents reacted with alpha-halocarbonyl compounds in the presence of a metal catalyst NATIONAL INSTITUTES OF HEALTH 2002-12-19 US disclosed
US-4479016-A Ethoxylates of diacetylene alcohols and the use of these compounds as surfactants BASF AKTIENGESELLSCHAFT (DE) 1984-10-23 US disclosed
US-4081468-A HERBICIDES STAUFFER CHEMICAL COMPANY (US) 1978-03-28 US disclosed