Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | HTT | P42858 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.41 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.41 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.41 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31267549 | 0.91 | NPC1 (0.51) | NPC1RAB9APOLBL3MBTL1LMNA | |
| SCHEMBL672147 | 0.91 | NPC1 (0.51) | NPC1RAB9APOLBL3MBTL1LMNA | |
| SCHEMBL674407 | 0.84 | NPC1 (0.53) | NPC1RAB9APOLBTDP1LMNA | |
| SCHEMBL29388780 | 0.84 | NPC1 (0.53) | NPC1RAB9APOLBTDP1LMNA | |
| SCHEMBL30772443 | 0.84 | NPC1 (0.53) | NPC1RAB9APOLBTDP1LMNA | |
| SCHEMBL709920 | 0.82 | NPC1 (0.56) | NPC1RAB9APOLBTDP1LMNA | |
| SCHEMBL10744136 | 0.82 | NPC1 (0.56) | NPC1RAB9APOLBTDP1LMNA | |
| SCHEMBL710157 | 0.82 | NPC1 (0.56) | NPC1RAB9APOLBTDP1LMNA | |
| SCHEMBL7649641 | 0.82 | NPC1 (0.56) | NPC1RAB9APOLBTDP1LMNA | |
| SCHEMBL9628169 | 0.82 | NPC1 (0.56) | NPC1RAB9APOLBTDP1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7968632-B2 | Polycarbonate resin composition and process for producing thereof | MITSUBISHI ENGINEERING-PLASTICS CORPORATION (JP) | 2011-06-28 | — | — | US | disclosed |
| EP-1892266-B1 | POLYCARBONATE RESIN COMPOSITION AND MOLDED ARTICLES | MITSUBISHI ENG PLASTICS CORP (JP) | 2010-07-21 | — | — | EP | disclosed |
| US-20090186967-A1 | Polycarbonate resin composition and process for producing thereof | MITSUBISHI ENGINEERING PLASTICS CORPORATION (JP) | 2009-07-23 | — | — | US | disclosed |
| EP-1892266-A1 | POLYCARBONATE RESIN COMPOSITION AND MOLDED ARTICLES | Mitsubishi Engineering-Plastics Corporation (JP) | 2008-02-27 | — | — | EP | disclosed |
| US-6762250-B2 | TRANSPARENCY, FLUIDITY; CONTAINING POLYSILOXANE HAVING AT LEAST AROMATIC HYDROCARBON FUNCTIONALITY, CARBOXYLIC ACID ESTER AND/OR ETHER LINKAGES AND PHOSPHORIC ESTER GROUP ATTACHMENT | MITSUBISHI ENGINEERING-PLASTICS CORPORATION (JP) | 2004-07-13 | — | — | US | disclosed |
| US-6727294-B2 | RADIATION TRANSPARENT MOLDING MATERIALS | MITSUBISHI ENGINEERING-PLASTICS CORPORATION (JP) | 2004-04-27 | — | — | US | disclosed |
| US-20040054116-A1 | Polycarbonate resin composition | MITSUBISHI ENGINEERING-PLASTICS CORPORATION | 2004-03-18 | — | — | US | disclosed |
| US-20010034419-A1 | Radiation transparent molding materials | MITSUBISHI ENGINEERING-PLASTICS CORPORATION (JP) | 2001-10-25 | — | — | US | disclosed |