Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CACNA2D1 | P54289 | 2/20 | 0.37 |
| ▸ | CACNB3 | P54284 | 1/20 | 0.37 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.37 |
| ▸ | PGR | P06401 | 1/20 | 0.37 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.37 |
| ▸ | HTR2B | P41595 | 1/20 | 0.37 |
| ▸ | CACNA2D2 | Q9NY47 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16453428 | 0.97 | TDP1 (0.46) | TDP1SMN1; SMN2SLC22A6CYP1A2CACNA2D1 | |
| SCHEMBL17679177 | 0.97 | TDP1 (0.46) | TDP1SMN1; SMN2SLC22A6CYP1A2CACNA2D1 | |
| SCHEMBL148545 | 0.97 | TDP1 (0.46) | TDP1SMN1; SMN2SLC22A6CYP1A2CACNA2D1 | |
| SCHEMBL2346353 | 0.82 | TDP1 (0.42) | TDP1SMN1; SMN2SLC22A6CYP1A2CACNA2D1 | |
| SCHEMBL14423824 | 0.80 | TDP1 (0.40) | TDP1SMN1; SMN2SLC22A6CYP1A2CACNA2D1 | |
| SCHEMBL304303 | 0.80 | SLC22A6 (0.50) | TDP1SMN1; SMN2SLC22A6CYP1A2CACNA2D1 | |
| SCHEMBL5077944 | 0.80 | SLC22A6 (0.50) | TDP1SMN1; SMN2SLC22A6CYP1A2CACNA2D1 | |
| SCHEMBL2348507 | 0.79 | SLC22A6 (0.39) | TDP1SMN1; SMN2SLC22A6CACNA2D1CACNB3 | |
| SCHEMBL2348670 | 0.79 | ALDH1A1 (0.50) | TDP1CYP1A2TP53 | |
| SCHEMBL25397374 | 0.76 | TDP1 (0.46) | TDP1SMN1; SMN2SLC22A6CYP1A2CACNA2D1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6686133-B2 | CONTAINING LIGHT-INSENSITIVE SILVER SALTS OF ORGANIC CARBOXYLIC ACIDS WITH ONE OR MORE CARBOXYLIC ACID AND A BINDER, EXCLUSIVE OF SILVER SUCCINATE SIMILAR COMPOUNDS | AGFA-GEVAERT (BE) | 2004-02-03 | — | — | US | disclosed |