SCHEMBL148545

SCHEMBL148545

CC(CC(=O)O)C(C)C(=O)O

nearest known ligand 0.52

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.46
SMN1; SMN2 Q16637 1/20 0.43
SLC22A6 Q4U2R8 1/20 0.41
CYP1A2 P05177 1/20 0.39
TP53 P04637 1/20 0.38
CACNA2D1 P54289 2/20 0.38
CACNB3 P54284 1/20 0.38
CACNA1C Q13936 1/20 0.38
PGR P06401 1/20 0.38
ADRA1A P35348 1/20 0.38
HTR2B P41595 1/20 0.38
CACNA2D2 Q9NY47 1/20 0.38
FOLH1 Q04609 1/20 0.37
MAPT P10636 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17679177 1.00 TDP1 (0.46) TDP1SMN1; SMN2SLC22A6CYP1A2TP53
SCHEMBL16453428 1.00 TDP1 (0.46) TDP1SMN1; SMN2SLC22A6CYP1A2TP53
SCHEMBL6738773 0.97 TDP1 (0.43) TDP1SMN1; SMN2SLC22A6CYP1A2TP53
SCHEMBL2346353 0.84 TDP1 (0.42) TDP1SMN1; SMN2SLC22A6CYP1A2TP53
SCHEMBL14423824 0.82 TDP1 (0.40) TDP1SMN1; SMN2SLC22A6CYP1A2TP53
SCHEMBL5077944 0.82 SLC22A6 (0.50) TDP1SMN1; SMN2SLC22A6CYP1A2CACNA2D1
SCHEMBL304303 0.82 SLC22A6 (0.50) TDP1SMN1; SMN2SLC22A6CYP1A2CACNA2D1
SCHEMBL2348507 0.81 SLC22A6 (0.39) TDP1SMN1; SMN2SLC22A6CACNA2D1CACNB3
SCHEMBL2348670 0.81 ALDH1A1 (0.50) TDP1CYP1A2TP53
SCHEMBL25397374 0.78 TDP1 (0.46) TDP1SMN1; SMN2SLC22A6CYP1A2TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 232 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240051212-A1 IMPROVED POLYESTER COMPOSITION FOR EXTRUSION BLOW MOLDED CONTAINERS AURIGA POLYMERS INC (US) 2024-02-15 US claimed
CN-117062894-A Coolant with improved temperature stability 巴斯夫欧洲公司 2023-11-14 CN claimed
EP-4267651-A1 IMPROVED POLYESTER COMPOSITION FOR EXTRUSION BLOW MOLDED CONTAINERS Auriga Polymers, Inc. (US) 2023-11-01 EP claimed
CN-116635449-A Improved polyester compositions for extrusion blow molded containers 奥里格聚合物股份有限公司 2023-08-22 CN claimed
WO-2023114069-A1 IMPROVED POLYESTER COMPOSITION FOR EXTRUSION BLOW MOLDED CONTAINERS AURIGA POLYMERS, INC. (US) 2023-06-22 WO claimed
WO-2022140183-A1 IMPROVED POLYESTER COMPOSITION FOR EXTRUSION BLOW MOLDED CONTAINERS AURIGA POLYMERS, INC. (US) 2022-06-30 WO claimed
US-11324827-B2 Multifunctionalized polyethylene glycol derivative and preparation method therefor XIAMEN SINOPEG BIOTECH CO., LTD. (CN) 2022-05-10 US claimed
CN-110643032-B Eight-arm polyethylene glycol, preparation method, functionalized derivative and modified biologically-relevant substance 厦门赛诺邦格生物科技股份有限公司 2022-01-28 CN claimed
CN-110643032-A Eight-arm polyethylene glycol, preparation method, functionalized derivative and modified biologically-relevant substance 厦门赛诺邦格生物科技股份有限公司 2020-01-03 CN claimed
US-20170312363-A1 MULTIFUNCTIONALIZED POLYETHYLENE GLYCOL DERIVATIVE AND PREPARATION METHOD THEREFOR XIAMEN SINOPEG BIOTECH CO., LTD. (CN) 2017-11-02 US claimed
CN-104530417-B A kind of multiple functionalized H types polyethyleneglycol derivative and preparation method thereof 厦门赛诺邦格生物科技股份有限公司 2017-09-08 CN claimed
CN-105980489-A Graffiti removal compositions and the use thereof 加迪特解决方案有限公司 2016-09-28 CN claimed
EP-2325228-A1 An aliphatic-aromatic copolyster, the preparation method and the use thereof Zhejiang Hangzhou Xinfu Pharmaceutical Co. Ltd (CN) 2011-05-25 EP claimed
EP-1062270-A1 LIGHT AND THERMALLY STABLE POLYAMIDE BASF CORPORATION (US) 2000-12-27 EP claimed
WO-1999046323-A1 LIGHT AND THERMALLY STABLE POLYAMIDE BASF CORPORATION (US) 1999-09-16 WO claimed
CN-122095025-A Polyamide composition and molded article 2026-05-26 CN disclosed
CN-111793331-B Biodegradable in-situ nanocomposite and preparation method and application thereof 浙江恒逸石化研究院有限公司 2026-05-15 CN disclosed
US-4101528-A FLAME RETARDANT AVTEX FIBERS INC. (US) 1978-07-18 US disclosed
US-4059546-A Textile fiber blend comprising cellulosic fibers and ethylene 2,6-naphthalene dicarboxylate-halogenated comonomers copolyester fibers AVTEX FIBERS INC. (US) 1977-11-22 US disclosed
US-4037112-A Apparatus for crosslinking ultraviolet light curable coatings PPG INDUSTRIES, INC. (US) 1977-07-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11324827-B2 Multifunctionalized polyethylene glycol derivative and preparation method therefor HDGF, F11, F12 TDP1 4223/4885SMN1; SMN2 3017/4885SLC22A6 4107/4885
US-20170312363-A1 MULTIFUNCTIONALIZED POLYETHYLENE GLYCOL DERIVATIVE AND PREPARATION METHOD THEREFOR HDGF, F11, F12 TDP1 4223/4885SMN1; SMN2 3017/4885SLC22A6 4107/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.