Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH1 | P35367 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | SCN1A | P35498 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.42 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 9/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 8/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.40 |
| ▸ | ESR1 | P03372 | 1/20 | 0.37 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6738802 | 0.82 | SLC18A3 (0.42) | HRH1MEN1LMNACYP2D6SCN1A | |
| SCHEMBL27998093 | 0.81 | KDM4E (0.50) | MEN1LMNAKMT2AESR1TRPM8 | |
| SCHEMBL3544485 | 0.74 | SLC18A3 (0.48) | HRH1MEN1LMNACYP2D6SCN1A | |
| SCHEMBL3837450 | 0.74 | SLC6A2 (0.62) | HRH1MEN1LMNACYP2D6SCN1A | |
| Hydrochloric Acid SCHEMBL18263847 | 0.72 | SLC6A2 (0.60) | HRH1MEN1LMNACYP2D6SCN1A | |
| SCHEMBL5691237 | 0.71 | MAOA (0.39) | SLC6A4SLC6A2SLC6A3SIGMAR1TRPM8 | |
| SCHEMBL4010135 | 0.71 | SLC18A3 (0.45) | HRH1MEN1LMNACYP2D6SCN1A | |
| SCHEMBL22634123 | 0.71 | SLC18A3 (0.45) | HRH1MEN1LMNACYP2D6SCN1A | |
| SCHEMBL28054166 | 0.71 | SLC18A3 (0.45) | HRH1MEN1LMNACYP2D6SCN1A | |
| SCHEMBL8553350 | 0.70 | SLC6A4 (0.51) | HRH1MEN1LMNACYP2D6SCN1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1899331-A1 | HOMOMORPHOLINE OXAZOLIDINONES AS ANTIBACTERIAL AGENTS | Pharmacia & Upjohn Company LLC (US) | 2008-03-19 | — | — | EP | disclosed |
| WO-2007000644-A1 | HOMOMORPHOLINE OXAZOLIDINONES AS ANTIBACTERIAL AGENTS | PHARMACIA & UPJOHN COMPANY LLC (US) | 2007-01-04 | — | — | WO | disclosed |