Known targets — ChEMBL curated mechanism
ACHECHKACHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGHRH2OPRM1
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL266061 | 0.97 | — | — | |
| Hydrochloric Acid SCHEMBL5316443 | 0.94 | ALDH1A1 (0.34) | ALDH1A1LMNAHTTSMN1; SMN2 | |
| Iodide SCHEMBL8679192 | 0.94 | ALDH1A1 (0.34) | ALDH1A1LMNAHTTSMN1; SMN2MAPT | |
| Bromide SCHEMBL17335765 | 0.75 | ALDH1A1 (0.36) | ALDH1A1LMNAHTTSMN1; SMN2 | |
| SCHEMBL5176797 | 0.71 | ALDH1A1 (0.38) | ALDH1A1LMNAHTTSMN1; SMN2 | |
| SCHEMBL98364 | 0.71 | — | — | |
| Bromide SCHEMBL28936676 | 0.71 | ALDH1A1 (0.34) | ALDH1A1LMNAHTTSMN1; SMN2 | |
| Bromide SCHEMBL31372219 | 0.71 | ALDH1A1 (0.34) | ALDH1A1LMNAHTTSMN1; SMN2 | |
| Bromide SCHEMBL11430512 | 0.71 | ALDH1A1 (0.34) | ALDH1A1LMNAHTTSMN1; SMN2 | |
| Bromide SCHEMBL10537002 | 0.70 | LMNA (0.34) | ALDH1A1LMNAHTTSMN1; SMN2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6680286-B1 | CONTAINING AN ORGANIC POLYELECTROLYTE BUILDER, QUATERNARY AMMONIUM ACRYLIC POLYMERS, WHICH ARE ESPECIALLY USEFUL FOR WASHING CLOTHES | SANYO CHEMICAL INDUSTRIES, LTD. (JP) | 2004-01-20 | — | — | US | disclosed |