Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE3B | Q13370 | 3/20 | 0.41 |
| ▸ | PDE3A | Q14432 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 4/20 | 0.38 |
| ▸ | PKM | P14618 | 2/20 | 0.38 |
| ▸ | SRC | P12931 | 2/20 | 0.38 |
| ▸ | BRD4 | O60885 | 1/20 | 0.36 |
| ▸ | PRKACA | P17612 | 1/20 | 0.36 |
| ▸ | PRKACG | P22612 | 1/20 | 0.36 |
| ▸ | PRKACB | P22694 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.35 |
| ▸ | CACNG8 | Q8WXS5 | 1/20 | 0.35 |
| ▸ | GFER | P55789 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2894232 | 0.83 | PDE3B (0.50) | PDE3BPDE3AGAAPKMMEN1 | |
| SCHEMBL1829719 | 0.73 | GRIN2D (0.50) | PDE3BPDE3AGAAPKMSRC | |
| SCHEMBL1115539 | 0.73 | GRIA1 (0.50) | PDE3BPDE3AGAAPKMMEN1 | |
| SCHEMBL3341909 | 0.73 | CASP7 (0.49) | PDE3BPDE3AGAAPKMMEN1 | |
| SCHEMBL1827312 | 0.73 | ALDH1A1 (0.53) | PDE3BPDE3AGAAPKMALDH1A1 | |
| SCHEMBL17758383 | 0.73 | PDE3B (0.41) | PDE3BPDE3AGAAPKMALDH1A1 | |
| SCHEMBL11317347 | 0.72 | IDO1 (0.46) | PDE3BPDE3AGAAPKMMEN1 | |
| SCHEMBL3876188 | 0.71 | SRC (0.64) | GAAPKMSRCPRKACAPRKACG | |
| SCHEMBL3876544 | 0.71 | SRC (0.64) | GAAPKMSRCPRKACAPRKACG | |
| SCHEMBL17758363 | 0.71 | PDE3B (0.36) | PDE3BPDE3AGAAPKMMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040107518-A1 | Hetero-anellated ortho-aminophenols and their use as dye components | CLARIANT FINANCE (BVI) LIMITED (BR) | 2004-06-10 | — | — | US | disclosed |
| EP-1335905-A1 | HETERO-ANELLATED ORTHO-AMINOPHENOLS AND THEIR USE AS DYE COMPONENTS | Clariant International Ltd. (CH) | 2003-08-20 | — | — | EP | disclosed |
| WO-2002038549-A1 | HETERO-ANELLATED ORTHO-AMINOPHENOLS AND THEIR USE AS DYE COMPONENTS | CLARIANT FINANCE (BVI) LTD. (GB) | 2002-05-16 | — | — | WO | disclosed |