Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STS | P08842 | 1/20 | 0.48 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.41 |
| ▸ | MAPT | P10636 | 5/20 | 0.41 |
| ▸ | NPC1 | O15118 | 6/20 | 0.41 |
| ▸ | RAB9A | P51151 | 5/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 3/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | STAT1 | P42224 | 1/20 | 0.39 |
| ▸ | CASP3 | P42574 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL761455 | 0.84 | NPC1 (0.55) | ALDH1A1KDM4EMAPTNPC1RAB9A | |
| SCHEMBL16372524 | 0.79 | STS (0.76) | STSPIN1ALDH1A1KDM4EMAPT | |
| SCHEMBL17740855 | 0.79 | STS (0.58) | STSALDH1A1KDM4EMAPTNPC1 | |
| SCHEMBL6981957 | 0.77 | CA1 (0.40) | ALDH1A1KDM4ENPC1RAB9AHPGD | |
| SCHEMBL1805795 | 0.77 | CYP11B1 (0.48) | ALDH1A1KDM4EHPGDCYP3A4PTGS1 | |
| SCHEMBL1806097 | 0.75 | ERN1 (0.47) | ALDH1A1MAPTHPGDCYP3A4CYP11B1 | |
| SCHEMBL6740241 | 0.75 | ACVR1 (0.48) | PIN1ALDH1A1KDM4EMAPTNPC1 | |
| SCHEMBL18872545 | 0.75 | STS (0.66) | STSALDH1A1KDM4EMAPTNPC1 | |
| SCHEMBL9172136 | 0.75 | CA1 (0.51) | ALDH1A1CYP3A4CYP11B1CYP11B2CYP17A1 | |
| SCHEMBL6741783 | 0.75 | CYP19A1 (0.49) | PIN1ALDH1A1MEN1CYP3A4CYP11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6689798-B2 | STEROID ALPHA-HYDROXYLASE AND STEROID LYASE INHIBITORS | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2004-02-10 | — | — | US | disclosed |
| US-20030149079-A1 | Novel benzofuran derivatives | DAIICHI PHARMACEUTICAL CO., LTD. | 2003-08-07 | — | — | US | disclosed |
| EP-1283208-A1 | NOVEL BENZOFURAN DERIVATIVES | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2003-02-12 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030149079-A1 | Novel benzofuran derivatives | CYP17A1, CYP21A2, HSD17B7 | STS 38/4885PIN1 585/4885ALDH1A1 119/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.