Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.59 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.54 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | HTR3A | P46098 | 1/20 | 0.36 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.35 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | AS3MT | Q9HBK9 | 1/20 | 0.35 |
| ▸ | ADAM17 | P78536 | 2/20 | 0.34 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.34 |
| ▸ | WEE1 | P30291 | 1/20 | 0.34 |
| ▸ | MMP9 | P14780 | 1/20 | 0.34 |
| ▸ | MMP1 | P03956 | 1/20 | 0.34 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6236659 | 0.95 | MAPK1 (0.57) | MAPK1HSD17B10CYP2C9NR1I2MEN1 | |
| SCHEMBL6240041 | 0.89 | MAPK1 (0.59) | MAPK1HSD17B10CYP2C9NR1I2MEN1 | |
| SCHEMBL6236709 | 0.88 | MAPK1 (0.57) | MAPK1HSD17B10CYP2C9NR1I2MEN1 | |
| SCHEMBL6235652 | 0.88 | MAPK1 (0.68) | MAPK1HSD17B10CYP2C9NR1I2MEN1 | |
| SCHEMBL6235658 | 0.87 | MAPK1 (0.57) | MAPK1HSD17B10CYP2C9NR1I2MEN1 | |
| SCHEMBL6737830 | 0.85 | MAPK1 (0.61) | MAPK1HSD17B10CYP2C9NR1I2MEN1 | |
| SCHEMBL6232411 | 0.85 | MAPK1 (0.67) | MAPK1HSD17B10CYP2C9NR1I2MEN1 | |
| SCHEMBL6739082 | 0.85 | MAPK1 (0.67) | MAPK1HSD17B10CYP2C9NR1I2MEN1 | |
| SCHEMBL6235598 | 0.85 | MAPK1 (0.56) | MAPK1HSD17B10CYP2C9NR1I2MEN1 | |
| SCHEMBL6234490 | 0.85 | MAPK1 (0.64) | MAPK1HSD17B10CYP2C9NR1I2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1535151-A | Novel anti-infectives | ʷ��˿�������ȳ�ķ����˾ | 2004-10-06 | — | — | CN | claimed |
| US-20040147739-A1 | Novel anti-infectives | SMITHKLINE BEECHAM CORPORATION | 2004-07-29 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040147739-A1 | Novel anti-infectives | RPL5, RPL7, RPL35 | MAPK1 3699/4885HSD17B10 1428/4885CYP2C9 1218/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.