Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 1/20 | 0.56 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.46 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | NFKBIA | P25963 | 1/20 | 0.44 |
| ▸ | RELA | Q04206 | 1/20 | 0.44 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL425784 | 0.82 | CYP2D6 (0.58) | CYP2D6CYP2C9CYP2C19KDM4EKMT2A | |
| SCHEMBL24254325 | 0.77 | CYP2D6 (0.67) | CYP2D6CYP2C9CYP2C19KDM4EKMT2A | |
| SCHEMBL10490753 | 0.77 | CYP2D6 (0.51) | CYP2D6CYP2C9CYP2C19KDM4EKMT2A | |
| SCHEMBL1863910 | 0.74 | CYP2D6 (0.62) | CYP2D6CYP2C9CYP2C19KDM4EKMT2A | |
| SCHEMBL1164889 | 0.74 | CYP2D6 (0.62) | CYP2D6CYP2C9CYP2C19KDM4EKMT2A | |
| SCHEMBL28978077 | 0.74 | CYP2D6 (0.62) | CYP2D6CYP2C9CYP2C19KDM4EKMT2A | |
| SCHEMBL8232303 | 0.74 | CYP2D6 (0.62) | CYP2D6CYP2C9CYP2C19KDM4EKMT2A | |
| SCHEMBL7455235 | 0.74 | CYP2D6 (0.62) | CYP2D6CYP2C9CYP2C19KDM4EKMT2A | |
| SCHEMBL4433902 | 0.74 | CYP2D6 (0.62) | CYP2D6CYP2C9CYP2C19KDM4EKMT2A | |
| SCHEMBL28314029 | 0.74 | CYP2D6 (0.62) | CYP2D6CYP2C9CYP2C19KDM4EKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030171595-A1 | Thienylsulphonylamino(thio)carbonyl compounds | MULLER KLAUS-HELMUT (DE) | 2003-09-11 | — | — | US | claimed |
| US-20030004354-A1 | Thienylsulphonylamino(thio)carbonyl compounds | MULLER KLAUS-HELMUT (DE) | 2003-01-02 | — | — | US | claimed |
| EP-0942908-B1 | THIENYLSULFONYLAMINO(THIO)CARBONYL COMPOUNDS | BAYER AG (DE) | 2002-02-13 | — | — | EP | claimed |
| US-6686478-B2 | NOVEL INTERMEDIATES FOR THEIR PREPARATION; HERBICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 2004-02-03 | — | — | US | disclosed |
| US-6686478-B2 | NOVEL INTERMEDIATES FOR THEIR PREPARATION; HERBICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 2004-02-03 | — | — | US | disclosed |
| US-6686478-B2 | NOVEL INTERMEDIATES FOR THEIR PREPARATION; HERBICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 2004-02-03 | — | — | US | disclosed |
| US-20030171595-A1 | Thienylsulphonylamino(thio)carbonyl compounds | MULLER KLAUS-HELMUT (DE) | 2003-09-11 | — | — | US | disclosed |
| US-20030171595-A1 | Thienylsulphonylamino(thio)carbonyl compounds | MULLER KLAUS-HELMUT (DE) | 2003-09-11 | — | — | US | disclosed |
| US-20030171595-A1 | Thienylsulphonylamino(thio)carbonyl compounds | MULLER KLAUS-HELMUT (DE) | 2003-09-11 | — | — | US | disclosed |
| US-6566536-B2 | Herbicides | BAYER AKTIENGESELLSCHAFT (DE) | 2003-05-20 | — | — | US | disclosed |
| US-6566536-B2 | Herbicides | BAYER AKTIENGESELLSCHAFT (DE) | 2003-05-20 | — | — | US | disclosed |
| US-20030004354-A1 | Thienylsulphonylamino(thio)carbonyl compounds | MULLER KLAUS-HELMUT (DE) | 2003-01-02 | — | — | US | disclosed |
| US-20030004354-A1 | Thienylsulphonylamino(thio)carbonyl compounds | MULLER KLAUS-HELMUT (DE) | 2003-01-02 | — | — | US | disclosed |
| CN-1088705-C | Thiophenesulfonylamino carbonyl compounds | BAYER AG (DE) | 2002-08-07 | — | — | CN | disclosed |
| US-6383988-B1 | HERBICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 2002-05-07 | — | — | US | disclosed |
| US-6383988-B1 | HERBICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 2002-05-07 | — | — | US | disclosed |
| EP-0942908-B1 | THIENYLSULFONYLAMINO(THIO)CARBONYL COMPOUNDS | BAYER AG (DE) | 2002-02-13 | — | — | EP | disclosed |
| CN-1239960-A | Thiophenesulfonylamino carbonyl compounds | BAYER AG (DE) | 1999-12-29 | — | — | CN | disclosed |
| EP-0942908-A1 | THIENYLSULFONYLAMINO(THIO)CARBONYL COMPOUNDS | BAYER AG (DE) | 1999-09-22 | — | — | EP | disclosed |
| WO-1998024787-A1 | THIENYLSULFONYLAMINO(THIO)CARBONYL COMPOUNDS | BAYER AKTIENGESELLSCHAFT (DE) | 1998-06-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030171595-A1 | Thienylsulphonylamino(thio)carbonyl compounds | CBR3, CBR1, QSOX1 | CYP2D6 135/4885CYP2C9 95/4885CYP2C19 448/4885 |
| US-20030004354-A1 | Thienylsulphonylamino(thio)carbonyl compounds | CBR3, CBR1, QSOX1 | CYP2D6 135/4885CYP2C9 95/4885CYP2C19 448/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.