SCHEMBL6740405

SCHEMBL6740405

CCOC(=O)CCC(F)(F)C(F)(F)C(F)(F)C(F)(F)C(=O)OCC

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TRPA1 O75762 1/20 0.38
ALDH1A1 P00352 1/20 0.38
CYP1A2 P05177 1/20 0.38
GAA P10253 2/20 0.36
MGAM O43451 1/20 0.36
SI P14410 1/20 0.36
MGAM2 Q2M2H8 1/20 0.36
MEN1 O00255 1/20 0.34
KMT2A Q03164 1/20 0.34
CYP4F2 P78329 4/20 0.33
CYP4A11 Q02928 4/20 0.33
PKM P14618 2/20 0.33
THRB P10828 1/20 0.33
HTT P42858 1/20 0.33
TSHR P16473 3/20 0.32
NR1I2 O75469 1/20 0.32
PGR P06401 1/20 0.32
ADORA3 P0DMS8 1/20 0.32
PTGS2 P35354 1/20 0.32
PDE4D Q08499 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9438339 0.89 ALDH1A1 (0.46) TRPA1ALDH1A1CYP1A2GAAMGAM
SCHEMBL9438259 0.88 ALDH1A1 (0.45) TRPA1ALDH1A1CYP1A2GAAMGAM
SCHEMBL6740413 0.87 TSHR (0.36) ALDH1A1CYP1A2GAAMEN1KMT2A
SCHEMBL17626380 0.84 TRPA1 (0.42) TRPA1ALDH1A1CYP1A2GAAMGAM
SCHEMBL6738109 0.83 GAA (0.39) TRPA1ALDH1A1CYP1A2GAAMGAM
SCHEMBL9854290 0.83 TRPA1 (0.41) TRPA1ALDH1A1CYP1A2GAAMGAM
SCHEMBL9854447 0.83 TRPA1 (0.41) TRPA1ALDH1A1CYP1A2GAAMGAM
SCHEMBL9438171 0.82 CYP1A2 (0.48) TRPA1ALDH1A1CYP1A2GAAMGAM
SCHEMBL27186828 0.82 ALDH1A1 (0.43) ALDH1A1GAAMGAMSIMGAM2
SCHEMBL8166839 0.80 ALDH1A1 (0.42) ALDH1A1GAAMGAMSIMGAM2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6689917-B2 Process for the preparation of perfluoroalkanones DAIKIN INDUSTRIES, LTD. (JP) 2004-02-10 US disclosed
US-20030144557-A1 Process for the preparation of perfluoroalkanones DAIKIN INDUSTRIES, LTD. (JP) 2003-07-31 US disclosed