SCHEMBL6740465

SCHEMBL6740465

CC(=O)Oc1c(C)cc(C2C(=O)Oc3c2cc(C(C)(C)C)cc3C(C)(C)C)cc1C.Cc1cc(C2C(=O)Oc3c2cc(C(C)(C)C)cc3C(C)(C)C)cc(C)c1OC(=O)C(C)(C)C

nearest known ligand 0.36

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
GABBR2 O75899 1/20 0.36
GABBR1 Q9UBS5 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL39328 0.96 GABBR2 (0.39) GABBR2GABBR1
SCHEMBL39102 0.96 GABBR2 (0.36) GABBR2GABBR1
SCHEMBL29413920 0.96 GABBR2 (0.36) GABBR2GABBR1
SCHEMBL3844045 0.90 GABBR2 (0.35) GABBR2GABBR1
SCHEMBL7647431 0.85 PPARG (0.31) GABBR2GABBR1
SCHEMBL3845418 0.84 GAA (0.34)
SCHEMBL5646348 0.83 GABBR2 (0.37) GABBR2GABBR1
SCHEMBL5566277 0.83 GABBR2 (0.37) GABBR2GABBR1
SCHEMBL3328968 0.83 GABBR2 (0.35) GABBR2GABBR1
SCHEMBL2612434 0.82 GABBR2 (0.36) GABBR2GABBR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6696570-B2 ESTER/AMIDE HINDERED AMINE LIGHT STABILIZERS (HALS) COMPOUNDS, ESTER/URETHANE HALS COMPOUNDS, ESTER/OXAMATE HALS COMPOUNDS, AMIDE/OXAMIDE HALS COMPOUNDS; PHOTOSTABILITY AND HEAT RESISTANCE FOR POLYMERS CYTEC TECHNOLOGY CORP. 2004-02-24 US disclosed
US-5489636-A STABILIZER FOR POLYOLEFINS AND OTHER NATURAL OR SYNTHETIC POLYMERS; MELTING THE STABILIZER AND RAPIDLY COOLING THE MELT, POURING THE COOL SURFACES; HEAT, OXIDATION AND RADIATION RESISTANCE CIBA-GEIGY CORPORATION (US) 1996-02-06 US disclosed