Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS1 | P29475 | 1/20 | 0.48 |
| ▸ | PARP10 | Q53GL7 | 6/20 | 0.47 |
| ▸ | PARP4 | Q9UKK3 | 2/20 | 0.47 |
| ▸ | PARP1 | P09874 | 2/20 | 0.47 |
| ▸ | CA2 | P00918 | 2/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.45 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.45 |
| ▸ | PARP16 | Q8N5Y8 | 1/20 | 0.45 |
| ▸ | PARP11 | Q9NR21 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2003577 | 0.89 | KMT2A (0.52) | KMT2AALDH1A1CYP3A4MAPTTDP1 | |
| SCHEMBL11150129 | 0.83 | MEN1 (0.50) | KMT2AALDH1A1CYP3A4MAPTTDP1 | |
| SCHEMBL9754092 | 0.80 | TSHR (0.55) | CA2CA1KMT2AALDH1A1CYP3A4 | |
| SCHEMBL3035986 | 0.80 | NPC1 (0.67) | KMT2AALDH1A1MAPTTDP1L3MBTL1 | |
| SCHEMBL6351346 | 0.80 | HSD17B3 (0.57) | CA2CA1ALDH1A1CYP3A4MAPT | |
| SCHEMBL15312863 | 0.80 | KMT2A (0.70) | KMT2AALDH1A1CYP3A4MAPTTDP1 | |
| SCHEMBL22919688 | 0.79 | PARP10 (0.50) | NOS1PARP10PARP4PARP1CA2 | |
| SCHEMBL11060731 | 0.78 | RAB9A (0.44) | KMT2AALDH1A1CYP3A4MAPTTDP1 | |
| SCHEMBL908578 | 0.78 | ERCC5 (0.62) | KMT2AALDH1A1MAPTL3MBTL1POLB | |
| SCHEMBL11813102 | 0.78 | NPC1 (0.64) | KMT2AALDH1A1MAPTTDP1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040107518-A1 | Hetero-anellated ortho-aminophenols and their use as dye components | CLARIANT FINANCE (BVI) LIMITED (BR) | 2004-06-10 | — | — | US | claimed |
| EP-1335905-A1 | HETERO-ANELLATED ORTHO-AMINOPHENOLS AND THEIR USE AS DYE COMPONENTS | Clariant International Ltd. (CH) | 2003-08-20 | — | — | EP | claimed |
| WO-2002038549-A1 | HETERO-ANELLATED ORTHO-AMINOPHENOLS AND THEIR USE AS DYE COMPONENTS | CLARIANT FINANCE (BVI) LTD. (GB) | 2002-05-16 | — | — | WO | claimed |
| US-3939140-A | Process for the preparation of a dyestuff consisting substantially of only unsymmetrical 1:2-chromium complex azo dyestuffs | HOECHST AKTIENGESELLSCHAFT (DT) | 1976-02-17 | — | — | US | claimed |
| US-20040107518-A1 | Hetero-anellated ortho-aminophenols and their use as dye components | CLARIANT FINANCE (BVI) LIMITED (BR) | 2004-06-10 | — | — | US | disclosed |
| EP-1335905-A1 | HETERO-ANELLATED ORTHO-AMINOPHENOLS AND THEIR USE AS DYE COMPONENTS | Clariant International Ltd. (CH) | 2003-08-20 | — | — | EP | disclosed |
| WO-2002038549-A1 | HETERO-ANELLATED ORTHO-AMINOPHENOLS AND THEIR USE AS DYE COMPONENTS | CLARIANT FINANCE (BVI) LTD. (GB) | 2002-05-16 | — | — | WO | disclosed |
| US-4322529-A | Tertiary-alkylamine salts of azine dyestuffs | CIBA-GEIGY CORPORATION (US) | 1982-03-30 | — | — | US | disclosed |
| US-4213897-A | FOR DYEING PAPER | SANDOZ LTD. (CH) | 1980-07-22 | — | — | US | disclosed |
| US-4213897-A | FOR DYEING PAPER | SANDOZ LTD. (CH) | 1980-07-22 | — | — | US | disclosed |
| US-3994872-A | SOLUBILITY | CIBA-GEIGY CORPORATION (US) | 1976-11-30 | — | — | US | disclosed |
| US-3939140-A | Process for the preparation of a dyestuff consisting substantially of only unsymmetrical 1:2-chromium complex azo dyestuffs | HOECHST AKTIENGESELLSCHAFT (DT) | 1976-02-17 | — | — | US | disclosed |