Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B3 | P37058 | 8/20 | 0.57 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.56 |
| ▸ | NPC1 | O15118 | 1/20 | 0.56 |
| ▸ | RAB9A | P51151 | 1/20 | 0.56 |
| ▸ | BLM | P54132 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | ABL1 | P00519 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | ALPI | P09923 | 1/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | ALPG | P10696 | 1/20 | 0.54 |
| ▸ | APEX1 | P27695 | 1/20 | 0.54 |
| ▸ | CASP3 | P42574 | 1/20 | 0.54 |
| ▸ | RECQL | P46063 | 1/20 | 0.54 |
| ▸ | CASP7 | P55210 | 1/20 | 0.54 |
| ▸ | CASP6 | P55212 | 1/20 | 0.54 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.54 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2003577 | 0.91 | KMT2A (0.52) | HSD17B3PTPN1NPC1RAB9AKDM4E | |
| SCHEMBL3987484 | 0.85 | NPC1 (0.65) | HSD17B3PTPN1NPC1RAB9ABLM | |
| Hydroquinone SCHEMBL1098186 | 0.83 | CA2 (0.54) | HSD17B3NPC1RAB9ABLMKDM4E | |
| SCHEMBL9754092 | 0.82 | TSHR (0.55) | NPC1RAB9AKDM4EALDH1A1TDP1 | |
| SCHEMBL3035986 | 0.82 | NPC1 (0.67) | NPC1RAB9AKDM4EALDH1A1GAA | |
| SCHEMBL13540737 | 0.81 | HSD17B3 (0.52) | HSD17B3PTPN1NPC1RAB9ABLM | |
| SCHEMBL908578 | 0.80 | ERCC5 (0.62) | NPC1RAB9AKDM4EALDH1A1POLB | |
| SCHEMBL11060731 | 0.80 | RAB9A (0.44) | HSD17B3PTPN1NPC1RAB9AKDM4E | |
| SCHEMBL8532385 | 0.80 | HSD17B3 (0.67) | HSD17B3PTPN1NPC1RAB9ABLM | |
| SCHEMBL3860105 | 0.80 | TPMT (0.48) | NPC1RAB9AKDM4EALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5071701-A | Containing silane substitutes cycloolefin prepared by metathesis ring-opening polymerization | B. F. GOODRICH CORPORATION (US) | 1991-12-10 | — | — | US | claimed |
| JP-2139289-A | — | — | None | — | — | JP | disclosed |
| US-20190119201-A1 | Inhibitors of Quorum Sensing Receptor LasR | WISCONSIN ALUMNI RESEARCH FOUNDATION | 2019-04-25 | — | — | US | disclosed |
| US-8796489-B2 | Ketobenzofuran derivatives, method for synthesizing same, and intermediates | SANOFI (FR) | 2014-08-05 | — | — | US | disclosed |
| US-20130012729-A1 | KETOBENZOFURAN DERIVATIVES, METHOD FOR SYNTHESIZING SAME, AND INTERMEDIATES | SANOFI (FR) | 2013-01-10 | — | — | US | disclosed |
| US-20050209478-A1 | Polydioxaborines | ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA | 2005-09-22 | — | — | US | disclosed |
| US-6916894-B2 | Polydioxaborines | NITTO DENKO CORPORATION (JP) | 2005-07-12 | — | — | US | disclosed |
| US-6703451-B2 | Superabsorbent resin composition | KAO CORPORATION (JP) | 2004-03-09 | — | — | US | disclosed |
| US-20030220500-A1 | An acrylic ester polymers comprise a 1,3,2- dioxaborine group in the side chain; soluble, film formers, and have semiconducting properties | NITTO DENKO CORPORATION (JP) | 2003-11-27 | — | — | US | disclosed |
| EP-0889063-B1 | Superabsorbent resin composition | KAO CORP (JP) | 2003-09-10 | — | — | EP | disclosed |
| JP-H02139289-A | THERMAL RECORDING MATERIAL | OJI PAPER CO LTD | 1990-05-29 | — | — | JP | disclosed |
| US-4923678-A | Low dielectric constant prepreg based on blends of polynorbornene and polyolefins derived form C2 -C4 monomers | THE B. F. GOODRICH COMPANY (US) | 1990-05-08 | — | — | US | disclosed |
| US-4923734-A | SANDWICHING A POLYOLEFIN FILM BETWEEN SILANE-TREATED FOIL AND A PREPREG OF NORBORNENE ALKENAMER COPOLYMER-IMPREGNATED CLOTH; PRINTED WIRING BOARDS; BONDING STRENGTH | THE B. F. GOODRICH COMPANY (US) | 1990-05-08 | — | — | US | disclosed |
| US-4910077-A | Impregnating a cloth with solution; laminating onto silane pretreated copper layer | B.F. GOODRICH COMPANY (US) | 1990-03-20 | — | — | US | disclosed |
| US-4902556-A | Multi-layer polynorbornene and epoxy laminates and process for making the same | THE B. F. GOODRICH COMPANY (US) | 1990-02-20 | — | — | US | disclosed |
| US-4891387-A | FOR REACTION INJECTION MOLDING | THE B. F. GOODRICH COMPANY (US) | 1990-01-02 | — | — | US | disclosed |
| EP-0330036-A1 | Process for the preparation of p-hydroxy-benzaldehydes | BAYER AG (DE) | 1989-08-30 | — | — | EP | disclosed |
| US-4258129-A | IMPROVE GREEN SHELF LIFE | FUJI PHOTO FILM CO., LTD. (JP) | 1981-03-24 | — | — | US | disclosed |
| US-4211839-A | SILVER HALIDE AND ORGANIC SILVER SALT PREPARED IN AN IMINO COMPOUND | FUJI PHOTO FILM CO., LTD. (JP) | 1980-07-08 | — | — | US | disclosed |
| US-4188212-A | BEZNOTRIAZOLE | FUJI PHOTO FILM CO., LTD. (JP) | 1980-02-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050209478-A1 | Polydioxaborines | DAXX, PUF60, DCAF7 | HSD17B3 3220/4885PTPN1 1151/4885NPC1 4515/4885 |
| US-20130012729-A1 | KETOBENZOFURAN DERIVATIVES, METHOD FOR SYNTHESIZING SAME, AND INTERMEDIATES | NNMT, DHPS, NDUFC1 | HSD17B3 1550/4885PTPN1 4282/4885NPC1 1470/4885 |
| US-20190119201-A1 | Inhibitors of Quorum Sensing Receptor LasR | FFAR1, CYSLTR1, LPAR1 | HSD17B3 3209/4885PTPN1 786/4885NPC1 3275/4885 |
| US-20030220500-A1 | An acrylic ester polymers comprise a 1,3,2- dioxaborine group in the side chain; soluble, film formers, and have semiconducting properties | DAXX, CAD, PUF60 | HSD17B3 1895/4885PTPN1 1511/4885NPC1 3999/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.