Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRHR1 | P34998 | 10/20 | 0.40 |
| ▸ | CNR1 | P21554 | 3/20 | 0.37 |
| ▸ | CNR2 | P34972 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6738122 | 0.83 | CRHR1 (0.43) | CRHR1CNR1 | |
| SCHEMBL7075525 | 0.81 | CNR1 (0.39) | CRHR1CNR1CNR2 | |
| SCHEMBL7216594 | 0.80 | CRHR1 (0.42) | CRHR1CNR1CNR2 | |
| SCHEMBL6739234 | 0.76 | CRHR1 (0.42) | CRHR1CNR1CNR2 | |
| SCHEMBL6738799 | 0.69 | CNR1 (0.41) | CRHR1CNR1CNR2 | |
| SCHEMBL6738646 | 0.69 | CRHR1 (0.39) | CRHR1CNR1 | |
| SCHEMBL6741034 | 0.68 | CRHR1 (0.39) | CRHR1 | |
| SCHEMBL6739618 | 0.65 | CRHR1 (0.39) | CRHR1CNR1 | |
| SCHEMBL6740017 | 0.65 | CRHR1 (0.40) | CRHR1 | |
| SCHEMBL6082515 | 0.57 | CRHR1 (0.45) | CRHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040023965-A1 | Imidazo-triazines as corticotropin releasing factor antagonists | GILLIGAN PAUL JOSEPH (US) | 2004-02-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040023965-A1 | Imidazo-triazines as corticotropin releasing factor antagonists | CRH, CRHR1, CRHR2 | CRHR1 2/4885CNR1 86/4885CNR2 163/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.