Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | RUNX1 | Q01196 | 2/20 | 0.41 |
| ▸ | CBFB | Q13951 | 2/20 | 0.41 |
| ▸ | GFER | P55789 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL224905 | 0.78 | APP (0.48) | ALDH1A1GAAMAPTHPGDHTT | |
| SCHEMBL6740529 | 0.78 | ALDH1A1 (0.41) | ALDH1A1GAAMAPTHPGDHTT | |
| SCHEMBL6721322 | 0.74 | ALDH1A1 (0.41) | ALDH1A1GAAMAPTHPGDHTT | |
| SCHEMBL12158655 | 0.74 | ALDH1A1 (0.38) | ALDH1A1GAAMAPTHPGDHTT | |
| SCHEMBL6742841 | 0.74 | ALDH1A1 (0.42) | ALDH1A1GAAMAPTHPGDHTT | |
| SCHEMBL10577638 | 0.74 | KIF11 (0.44) | ALDH1A1GAAMAPTHPGDHTT | |
| SCHEMBL9133011 | 0.72 | CSNK2A1 (0.51) | ALDH1A1GAAMAPTHPGDHTT | |
| SCHEMBL9134795 | 0.68 | IDO1 (0.42) | ALDH1A1GAAMAPTHPGDHTT | |
| SCHEMBL9134655 | 0.68 | ALDH1A1 (0.58) | ALDH1A1GAAMAPTHPGDHTT | |
| SCHEMBL9826277 | 0.68 | CYP2A6 (0.45) | ALDH1A1GAAMAPTHPGDHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6689771-B2 | TREATMENT OF RHEUMATOID ARTHRITIS, OSTEOARTHRITIS, PERIODONTITIS, GINGIVITIS, CORNEAL ULCERATION, SOLID TUMOR GROWTH | BRISTOL-MYERS SQUIBB PHARMA COMPANY | 2004-02-10 | — | — | US | disclosed |
| US-6376665-B1 | ANTIARTHRITIC AGENTS, ANTIINFLAMMATORY AGENTS | BRISTOL-MYERS SQUIBB PHARMA COMPANY | 2002-04-23 | — | — | US | disclosed |