Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 10/20 | 0.71 |
| ▸ | RARG | P13631 | 9/20 | 0.71 |
| ▸ | RARA | P10276 | 9/20 | 0.71 |
| ▸ | RXRA | P19793 | 11/20 | 0.48 |
| ▸ | RXRB | P28702 | 2/20 | 0.48 |
| ▸ | RXRG | P48443 | 2/20 | 0.48 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.45 |
| ▸ | CYP26A1 | O43174 | 3/20 | 0.44 |
| ▸ | CYP26B1 | Q9NR63 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | GMNN | O75496 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6740925 | 1.00 | RARB (0.71) | RARBRARGRARARXRARXRB | |
| SCHEMBL9205579 | 0.83 | RARB (1.00) | RARBRARGRARARXRARXRB | |
| SCHEMBL6430446 | 0.79 | RARB (0.64) | RARBRARGRARARXRARXRB | |
| SCHEMBL8522221 | 0.78 | RARB (0.58) | RARBRARGRARARXRARXRB | |
| SCHEMBL8522220 | 0.78 | RARB (0.58) | RARBRARGRARARXRARXRB | |
| SCHEMBL7746436 | 0.77 | RARB (0.53) | RARBRARGRARARXRARXRB | |
| SCHEMBL6737856 | 0.76 | RARB (0.72) | RARBRARGRARARXRARXRB | |
| SCHEMBL6737849 | 0.76 | RARB (0.72) | RARBRARGRARARXRARXRB | |
| SCHEMBL6737853 | 0.76 | RARB (0.72) | RARBRARGRARARXRARXRB | |
| SCHEMBL8735114 | 0.76 | RARB (0.64) | RARBRARGRARARXRARXRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6686386-B1 | COMBATING PHOTOINDUCED OR CHRONOLOGICAL AGEING OF SKIN WITH RETENOIC ACID RECEPTOR AGONIST | GALDERMA RESEARCH & DEVELOPMENT S.N.C. (FR) | 2004-02-03 | — | — | US | claimed |