Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 6/20 | 0.64 |
| ▸ | RARG | P13631 | 6/20 | 0.64 |
| ▸ | RARA | P10276 | 5/20 | 0.64 |
| ▸ | RXRA | P19793 | 10/20 | 0.50 |
| ▸ | RXRB | P28702 | 6/20 | 0.50 |
| ▸ | RXRG | P48443 | 5/20 | 0.50 |
| ▸ | CYP26B1 | Q9NR63 | 3/20 | 0.45 |
| ▸ | CYP26A1 | O43174 | 3/20 | 0.45 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.40 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7224461 | 0.85 | RARA (0.47) | RARBRARGRARARXRARXRB | |
| SCHEMBL6740925 | 0.79 | RARB (0.71) | RARBRARGRARARXRARXRB | |
| SCHEMBL6740919 | 0.79 | RARB (0.71) | RARBRARGRARARXRARXRB | |
| SCHEMBL5204128 | 0.79 | MAOB (0.48) | PTGER4PTGER2 | |
| SCHEMBL9205579 | 0.78 | RARB (1.00) | RARBRARGRARARXRARXRB | |
| SCHEMBL8690742 | 0.77 | RARB (0.49) | RARBRARGRARA | |
| SCHEMBL7999260 | 0.76 | RARB (0.64) | RARBRARGRARARXRARXRB | |
| SCHEMBL10459825 | 0.76 | RXRA (0.63) | RARBRARGRARARXRARXRB | |
| SCHEMBL7071780 | 0.75 | RXRA (0.52) | RARBRARGRARARXRARXRB | |
| SCHEMBL7071777 | 0.75 | RXRA (0.52) | RARBRARGRARARXRARXRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1567172-A2 | FORMULATIONS USEFUL AGAINST HEPATITIS C VIRUS INFECTIONS | GPC Biotech AG (DE) | 2005-08-31 | — | — | EP | disclosed |
| WO-2004050101-A3 | FORMULATIONS USEFUL AGAINST HEPATITIS C VIRUS INFECTIONS | AXXIMA PHARMACEUTICALS AG (DE) | 2004-09-10 | — | — | WO | disclosed |
| WO-2004050101-A2 | FORMULATIONS USEFUL AGAINST HEPATITIS C VIRUS INFECTIONS | GPC BIOTECH AG (DE) | 2004-06-17 | — | — | WO | disclosed |