Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 9/20 | 0.64 |
| ▸ | RARG | P13631 | 9/20 | 0.64 |
| ▸ | RARA | P10276 | 8/20 | 0.64 |
| ▸ | RXRA | P19793 | 13/20 | 0.47 |
| ▸ | RXRB | P28702 | 6/20 | 0.47 |
| ▸ | RXRG | P48443 | 5/20 | 0.47 |
| ▸ | CYP26A1 | O43174 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | GMNN | O75496 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9205579 | 0.78 | RARB (1.00) | RARBRARGRARARXRARXRB | |
| SCHEMBL6740925 | 0.76 | RARB (0.71) | RARBRARGRARARXRARXRB | |
| SCHEMBL6740919 | 0.76 | RARB (0.71) | RARBRARGRARARXRARXRB | |
| SCHEMBL1073661 | 0.74 | RARA (0.70) | RARBRARGRARARXRARXRB | |
| SCHEMBL728001 | 0.73 | RARB (0.74) | RARBRARGRARARXRARXRB | |
| SCHEMBL10937494 | 0.72 | RARA (0.54) | RARBRARGRARARXRARXRB | |
| SCHEMBL7753443 | 0.72 | RXRA (0.48) | RARBRARGRARARXRARXRB | |
| SCHEMBL10937497 | 0.72 | RARA (0.54) | RARBRARGRARARXRARXRB | |
| SCHEMBL8361355 | 0.71 | RARB (0.57) | RARBRARGRARARXRARXRB | |
| SCHEMBL8361347 | 0.71 | RARB (0.57) | RARBRARGRARARXRARXRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0879223-A1 | AROMATIC POLYCYCLIC RETINOID-TYPE DERIVATIVES, METHOD FOR PREPARING SAME, AND USE THEREOF FOR MAKING PHARMACEUTICAL AND COSMETIC COMPOSITIONS | Centre Europeen de Bioprospective -CEB (FR) | 1998-11-25 | — | — | EP | disclosed |
| WO-1997026237-A1 | AROMATIC POLYCYCLIC RETINOID-TYPE DERIVATIVES, METHOD FOR PREPARING SAME, AND USE THEREOF FOR MAKING PHARMACEUTICAL AND COSMETIC COMPOSITIONS | CENTRE EUROPEEN DE BIOPROSPECTIVE - CEB (FR) | 1997-07-24 | — | — | WO | disclosed |