SCHEMBL6740977

SCHEMBL6740977

N#CCCCCCN1CCCCCC1=O

nearest known ligand 0.50

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
MAPT P10636 1/20 0.50
L3MBTL1 Q9Y468 1/20 0.41
ADRA1B P35368 5/20 0.41
CYP1A2 P05177 1/20 0.40
CHRM2 P08172 1/20 0.40
CHRM4 P08173 1/20 0.40
CHRM5 P08912 1/20 0.40
CYP2D6 P10635 1/20 0.40
CHRM1 P11229 1/20 0.40
CYP2C9 P11712 1/20 0.40
CHRM3 P20309 1/20 0.40
CYP2C19 P33261 1/20 0.40
PIK3CD O00329 1/20 0.40
ADRA1A P35348 2/20 0.39
HRH3 Q9Y5N1 2/20 0.39
KMT2A Q03164 3/20 0.38
MEN1 O00255 2/20 0.38
MALT1 Q9UDY8 1/20 0.37
PKM P14618 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3936513 0.86 PIK3CD (0.48) MAPTADRA1BCYP1A2CHRM2CHRM4
SCHEMBL5081884 0.86 L3MBTL1 (0.46) MAPTL3MBTL1CYP1A2CHRM2CHRM4
SCHEMBL14408262 0.84 CHRM2 (0.46) MAPTL3MBTL1CYP1A2CHRM2CHRM4
SCHEMBL989008 0.80 PIK3CD (0.52) ADRA1BCYP1A2CHRM2CHRM4CHRM5
SCHEMBL5697292 0.80 PIK3CD (0.52) ADRA1BCYP1A2CHRM2CHRM4CHRM5
SCHEMBL31632694 0.80 PIK3CD (0.52) ADRA1BCYP1A2CHRM2CHRM4CHRM5
SCHEMBL19514132 0.80 PIK3CD (0.52) ADRA1BCYP1A2CHRM2CHRM4CHRM5
SCHEMBL11855053 0.79 ALOX5 (0.46) L3MBTL1ADRA1BPIK3CDHRH3KMT2A
SCHEMBL10816721 0.79 ALOX5 (0.46) L3MBTL1ADRA1BPIK3CDHRH3KMT2A
SCHEMBL11847945 0.79 ALOX5 (0.46) L3MBTL1ADRA1BPIK3CDHRH3KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6683179-B2 Preparation of caprolactam BASF AKTIENGESELLSCHAFT (DE) 2004-01-27 US disclosed
US-20030105322-A1 Method for producing caprolactam on the basis of 6-aminocapronitrile and subsequent purification by crystallization WURTZEL, ALAN 2003-06-05 US disclosed
EP-1280767-A1 METHOD FOR PRODUCING CAPROLACTAM ON THE BASIS OF 6-AMINOCAPRONITRILE AND SUBSEQUENT PURIFICATION BY CRYSTALLIZATION BASF AKTIENGESELLSCHAFT (DE) 2003-02-05 EP disclosed
WO-2001083443-A1 METHOD FOR PRODUCING CAPROLACTAM ON THE BASIS OF 6-AMINOCAPRONITRILE AND SUBSEQUENT PURIFICATION BY CRYSTALLIZATION BASF AKTIENGESELLSCHAFT (DE) 2001-11-08 WO disclosed