SCHEMBL6741022

SCHEMBL6741022

O=[N+]([O-])c1ccc(CCO)o1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 5/20 0.58
TDP1 Q9NUW8 4/20 0.46
L3MBTL1 Q9Y468 3/20 0.46
KMT2A Q03164 2/20 0.46
KDM4E B2RXH2 2/20 0.46
ALDH1A1 P00352 2/20 0.46
SMN1; SMN2 Q16637 2/20 0.46
MEN1 O00255 1/20 0.46
NPC1 O15118 1/20 0.46
MITF O75030 1/20 0.46
MAPT P10636 1/20 0.46
XBP1 P17861 1/20 0.46
RAB9A P51151 1/20 0.46
NPSR1 Q6W5P4 1/20 0.46
POLB P06746 3/20 0.45
TSHR P16473 1/20 0.44
GLO1 Q04760 1/20 0.44
HTT P42858 3/20 0.40
NFKB1 P19838 1/20 0.40
RECQL P46063 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1977597 0.84 LMNA (0.61) LMNATDP1L3MBTL1KMT2AKDM4E
SCHEMBL27512957 0.81 LMNA (0.58) LMNATDP1L3MBTL1KMT2AKDM4E
SCHEMBL14206944 0.81 LMNA (0.58) LMNATDP1L3MBTL1KMT2AKDM4E
SCHEMBL2094268 0.81 LMNA (0.58) LMNATDP1L3MBTL1KMT2AKDM4E
SCHEMBL11731878 0.80 LMNA (0.53) LMNATDP1L3MBTL1KMT2AKDM4E
SCHEMBL27971705 0.78 LMNA (0.54) LMNATDP1L3MBTL1KMT2AKDM4E
SCHEMBL2096072 0.78 LMNA (0.54) LMNATDP1L3MBTL1KMT2AKDM4E
SCHEMBL2813240 0.78 LMNA (0.63) LMNATDP1L3MBTL1KMT2AKDM4E
SCHEMBL9684997 0.77 LMNA (0.53) LMNATDP1L3MBTL1KMT2AKDM4E
SCHEMBL2097554 0.77 LMNA (0.53) LMNATDP1L3MBTL1KMT2AKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20040242591-A1 Oxazolidinone derivatives as pontential antimicrobials RANBAXY LABORATORIES LIMITED (IN) 2004-12-02 US disclosed
EP-1409464-A1 OXAZOLIDINONE DERIVATIVES AS POTENTIAL ANTIMICROBIALS RANBAXY LABORATORIES, LTD. (IN) 2004-04-21 EP disclosed
WO-2003008389-A1 OXAZOLIDINONE DERIVATIVES AS POTENTIAL ANTIMICROBIALS RANBAXY LABORATORIES LIMITED (IN) 2003-01-30 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040242591-A1 Oxazolidinone derivatives as pontential antimicrobials PDK4, OXA1L, PPARD LMNA 3499/4885TDP1 2252/4885L3MBTL1 2960/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.