SCHEMBL1977597

SCHEMBL1977597

O=[N+]([O-])c1ccc(CO)o1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 4/20 0.61
TDP1 Q9NUW8 4/20 0.44
L3MBTL1 Q9Y468 3/20 0.44
ALDH1A1 P00352 2/20 0.44
KMT2A Q03164 2/20 0.44
KDM4E B2RXH2 1/20 0.44
MEN1 O00255 1/20 0.44
NPC1 O15118 1/20 0.44
MITF O75030 1/20 0.44
MAPT P10636 1/20 0.44
XBP1 P17861 1/20 0.44
RAB9A P51151 1/20 0.44
SMN1; SMN2 Q16637 1/20 0.44
NPSR1 Q6W5P4 1/20 0.44
TSHR P16473 1/20 0.44
POLB P06746 3/20 0.43
GLO1 Q04760 1/20 0.42
HTT P42858 2/20 0.42
NFKB1 P19838 1/20 0.42
RECQL P46063 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6741022 0.84 LMNA (0.58) LMNATDP1L3MBTL1ALDH1A1KMT2A
SCHEMBL2813240 0.81 LMNA (0.63) LMNATDP1L3MBTL1ALDH1A1KMT2A
SCHEMBL31277119 0.81 ALDH1A1 (0.45) LMNATDP1L3MBTL1ALDH1A1KDM4E
SCHEMBL18459658 0.79 LMNA (0.61) LMNATDP1L3MBTL1ALDH1A1KMT2A
SCHEMBL5077061 0.79 LMNA (0.61) LMNATDP1L3MBTL1ALDH1A1KMT2A
SCHEMBL2056126 0.79 LMNA (0.61) LMNATDP1L3MBTL1ALDH1A1KMT2A
SCHEMBL4118512 0.79 LMNA (0.61) LMNATDP1L3MBTL1ALDH1A1KMT2A
SCHEMBL482336 0.79 LMNA (0.61) LMNATDP1L3MBTL1ALDH1A1KMT2A
SCHEMBL2089914 0.79 LMNA (0.61) LMNATDP1L3MBTL1ALDH1A1KMT2A
SCHEMBL5077063 0.79 LMNA (0.61) LMNATDP1L3MBTL1ALDH1A1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 171 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122011028-A Method for efficiently preparing various substituted chiral phosphoramides 上海交通大学 2026-05-12 CN claimed
CN-116637634-B Preparation and application of furanmethanol compound hydrogenolysis catalyst 南昌大学 2025-06-13 CN claimed
CN-119820898-A Forming method of hollow special-shaped carbon fiber composite material 天津工业大学 2025-04-15 CN claimed
CN-118084908-A Cyanine dye derivative and synthetic method and application thereof 山西大学 2024-05-28 CN claimed
CN-116637634-A Preparation and application of furanmethanol compound hydrogenolysis catalyst 南昌大学 2023-08-25 CN claimed
CN-122011028-A Method for efficiently preparing various substituted chiral phosphoramides 上海交通大学 2026-05-12 CN disclosed
US-12521397-B2 Nucleotide analogs THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2026-01-13 US disclosed
US-12350274-B2 Nucleotide analogs THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2025-07-08 US disclosed
CN-116637634-B Preparation and application of furanmethanol compound hydrogenolysis catalyst 南昌大学 2025-06-13 CN disclosed
CN-120040501-A Double phosphonic acid double salt containing acryloyloxy and quaternary ammonium cations 江苏海洋大学 2025-05-27 CN disclosed
CN-119820898-A Forming method of hollow special-shaped carbon fiber composite material 天津工业大学 2025-04-15 CN disclosed
CN-119060054-A Nitroaromatic ring substituted imidazopyrazine compound and preparation method and application thereof 南京中医药大学 2024-12-03 CN disclosed
US-4251524-A ANIMAL GROWTH REGULATORS BAYER AKTIENGESELLSCHAFT (DE) 1981-02-17 US disclosed
US-4200576-A CEPHALOSPORINS BAYER AKTIENGESELLSCHAFT (DE) 1980-04-29 US disclosed
EP-0002765-A1 Cephalosporin derivatives, process for their preparation and pharmaceutical compositions and their preparation HOECHST AKTIENGESELLSCHAFT (DE) 1979-07-11 EP disclosed
US-4152444-A RIFAMPICIN AND NITROFURANTOIN CIBA-GEIGY CORPORATION (US) 1979-05-01 US disclosed
US-4008256-A Esterification of furfuryl alcohol and its derivates KEMIRA OY (SF) 1977-02-15 US disclosed
US-3982007-A BENZISOTHIAZOLINONE DERIVATIVE, 2-NITROFURYL OR 2-NITROTHIENYL DERIVATIVE, ANTIMICROBIAL SANDOZ LTD. (CH) 1976-09-21 US disclosed
US-3956312-A ANTISECRETORY AGENT EGYT GYOGYSZERVEGYESZETI GYAR (HU) 1976-05-11 US disclosed
US-3910839-A Slime inhibitor for use in industrial water recirculating systems KEMIRA OY 1975-10-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12350274-B2 Nucleotide analogs NUDT1, DUT, DPYD LMNA 1406/4885TDP1 192/4885L3MBTL1 2022/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.