Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 9/20 | 0.45 |
| ▸ | CA1 | P00915 | 7/20 | 0.45 |
| ▸ | CA9 | Q16790 | 5/20 | 0.45 |
| ▸ | CA6 | P23280 | 3/20 | 0.45 |
| ▸ | PTGES2 | Q9H7Z7 | 3/20 | 0.45 |
| ▸ | CA5A | P35218 | 3/20 | 0.45 |
| ▸ | CA4 | P22748 | 2/20 | 0.45 |
| ▸ | CA12 | O43570 | 2/20 | 0.45 |
| ▸ | CA7 | P43166 | 2/20 | 0.45 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.45 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.44 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL14638222 | 0.98 | CA2 (0.45) | CA2CA1CA9CA6PTGES2 | |
| SCHEMBL15352818 | 0.85 | GABRA1 (0.46) | CA2CA1CA9CA6PTGES2 | |
| SCHEMBL5570050 | 0.84 | PTGES2 (0.42) | CA2CA1CA9CA6PTGES2 | |
| SCHEMBL10180071 | 0.82 | SLC6A2 (0.49) | CA2GABRA1GABRB2ATM | |
| SCHEMBL24879280 | 0.81 | GABRA1 (0.44) | CA2GABRA1GABRB2ATMGAA | |
| SCHEMBL4657831 | 0.81 | GABRA1 (0.48) | CA2GABRA1GABRB2ATM | |
| SCHEMBL10180745 | 0.81 | GABRA1 (0.44) | CA2GABRA1GABRB2ATM | |
| SCHEMBL301742 | 0.79 | CA2 (0.52) | CA2CA1CA9CA6PTGES2 | |
| SCHEMBL30096522 | 0.79 | CA2 (0.52) | CA2CA1CA9CA6PTGES2 | |
| Ammonia Solution, Strong SCHEMBL23749128 | 0.79 | GABRA1 (0.47) | CA2GABRA1GABRB2ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 61 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107496423-B | The purposes of 2- (benzyl (ethyl) amino) -5- (4- isobutyl-benzene sulfonamido) Nicotinicum Acidum or its salt | 江苏理工学院 | 2019-07-19 | — | — | CN | claimed |
| CN-107496423-A | The purposes of 2 (benzyl (ethyl) amino) 5 (4 isobutyl-benzene sulfonamido) Nicotinicum Acidum or its salt | 江苏理工学院 | 2017-12-22 | — | — | CN | claimed |
| CN-104024251-B | Benzenesulfonamide compounds and their use as therapeutic agents | 克赛农制药股份有限公司 | 2017-08-11 | — | — | CN | claimed |
| CN-104379559-B | Compound (I) | 葛兰素集团有限公司 | 2016-11-09 | — | — | CN | claimed |
| EP-2841416-A1 | NOVEL COMPOUNDS | Glaxo Group Limited (GB) | 2015-03-04 | — | — | EP | claimed |
| EP-2773637-A1 | BENZENESULFONAMIDE COMPOUNDS AND THEIR USE AS THERAPEUTIC AGENTS | Xenon Pharmaceuticals Inc. (CA) | 2014-09-10 | — | — | EP | claimed |
| EP-2760443-A1 | SULFONAMIDE COMPOUNDS AND THEIR USE IN THE MODULATION RETINOID - RELATED ORPHAN RECEPTOR | Glaxo Group Limited (GB) | 2014-08-06 | — | — | EP | claimed |
| WO-2013160418-A1 | NOVEL COMPOUNDS | GLAXO GROUP LIMITED (GB) | 2013-10-31 | — | — | WO | claimed |
| EP-2606096-A1 | CHLORINE-FREE INK AND COATING COMPOSITIONS&A METHOD FOR PRINTING ON UNTREATED POLYOLEFIN FILMS WITH IMPROVED ADHESION | Sun Chemical Corporation (US) | 2013-06-26 | — | — | EP | claimed |
| WO-2013064983-A1 | BENZENESULFONAMIDE COMPOUNDS AND THEIR USE AS THERAPEUTIC AGENTS | XENON PHARMACEUTICALS INC. (CA) | 2013-05-10 | — | — | WO | claimed |
| WO-2013045431-A1 | SULFONAMIDE COMPOUNDS AND THEIR USE IN THE MODULATION RETINOID - RELATED ORPHAN RECEPTOR | GLAXO GROUP LIMITED (GB) | 2013-04-04 | — | — | WO | claimed |
| WO-2012024472-A1 | CHLORINE-FREE INK AND COATING COMPOSITIONS & A METHOD FOR PRINTING ON UNTREATED POLYOLEFIN FILMS WITH IMPROVED ADHESION | SUN CHEMICAL CORPORATION (US) | 2012-02-23 | — | — | WO | claimed |
| EP-1976498-A2 | CHEMICAL COMPOUNDS | SmithKline Beecham Corporation (US) | 2008-10-08 | — | — | EP | claimed |
| WO-2007127505-A2 | USE OF SULFONAMIDE DERIVATIVES IN THE TREATMENT OF DISORDERS OF THE METABOLISM AND THE NERVOUS SYSTEM | SMITHKLINE BEECHAM CORPORATION (US) | 2007-11-08 | — | — | WO | claimed |
| EP-1165866-B1 | ABRASIVE FILAMENTS OF PLASTICIZED POLYAMIDES | DU PONT (US) | 2004-01-28 | — | — | EP | claimed |
| US-11446398-B2 | Regulated biocircuit systems | OBSIDIAN THERAPEUTICS, INC. (US) | 2022-09-20 | — | — | US | disclosed |
| CN-113896658-A | Method for synthesizing darunavir intermediate by using microchannel reactor | 上药康丽（常州）药业有限公司 | 2022-01-07 | — | — | CN | disclosed |
| EP-1725566-A1 | PROCESS FOR THE PREPARATION OF (3R,3AS,6AR)-HEXAHYDROFURO [2,3-B] FURAN-3-YL (1S,2R)-3-[[(4-AMINOPHENYL) SULFONYL] (ISOBUTYL) AMINO]-1-BENZYL-2-HYDROXYPROPYLCARBAMATE | Tibotec Pharmaceuticals Ltd. (IE) | 2006-11-29 | — | — | EP | disclosed |
| WO-2006114001-A1 | METHOD FOR IMPROVING PHARMACOKINETICS OF PROTEASE INHIBITORS AND PROTEASE INHIBITOR PRECURSORS | AMBRILIA BIOPHARMA INC. (CA) | 2006-11-02 | — | — | WO | disclosed |
| WO-2005063770-A1 | PROCESS FOR THE PREPARATION OF (3R,3AS,6AR)-HEXAHYDROFURO [2,3-B] FURAN-3-YL (1S,2R)-3-[[(4-AMINOPHENYL) SULFONYL] (ISOBUTYL) AMINO]-1-BENZYL-2-HYDROXYPROPYLCARBAMATE | TIBOTEC PHARMACEUTICALS LTD. (IE) | 2005-07-14 | — | — | WO | disclosed |