Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2A6 | P11509 | 6/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.56 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.56 |
| ▸ | CYP2B6 | P20813 | 2/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.56 |
| ▸ | PPARA | Q07869 | 1/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.40 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.40 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.40 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | FYN | P06241 | 1/20 | 0.38 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.38 |
| ▸ | KDR | P35968 | 1/20 | 0.38 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.37 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.37 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.37 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.36 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6739723 | 0.99 | CYP2A6 (0.55) | CYP2A6CYP3A4CYP2C9CYP2B6CYP2C19 | |
| SCHEMBL6741783 | 0.87 | CYP19A1 (0.49) | CYP2A6CYP3A4CYP19A1CYP11B1CYP11B2 | |
| SCHEMBL6740241 | 0.84 | ACVR1 (0.48) | CYP2A6CYP3A4CYP19A1CYP11B1CYP11B2 | |
| SCHEMBL6736802 | 0.82 | CYP19A1 (0.49) | CYP3A4CYP2C9CYP2B6CYP2C19PPARA | |
| SCHEMBL6740187 | 0.81 | TDO2 (0.48) | CYP3A4PPARAHDAC1CYP19A1CYP11B1 | |
| SCHEMBL6741025 | 0.81 | MIF (0.48) | CYP3A4CYP2C9CYP2B6CYP2C19CYP19A1 | |
| SCHEMBL6740852 | 0.81 | CYP3A4 (0.54) | CYP3A4CYP2C9CYP2B6CYP2C19PPARA | |
| SCHEMBL6741695 | 0.80 | TDO2 (0.47) | CYP3A4CYP2C9CYP2B6CYP2C19PPARA | |
| Bromide SCHEMBL6741296 | 0.80 | MIF (0.47) | CYP3A4CYP2C9CYP2B6CYP2C19CYP19A1 | |
| SCHEMBL6736043 | 0.80 | AXL (0.59) | CYP3A4CYP2C9CYP2B6CYP2C19CYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6689798-B2 | STEROID ALPHA-HYDROXYLASE AND STEROID LYASE INHIBITORS | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2004-02-10 | — | — | US | claimed |
| US-6689798-B2 | STEROID ALPHA-HYDROXYLASE AND STEROID LYASE INHIBITORS | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2004-02-10 | — | — | US | disclosed |
| US-20030149079-A1 | Novel benzofuran derivatives | DAIICHI PHARMACEUTICAL CO., LTD. | 2003-08-07 | — | — | US | disclosed |
| EP-1283208-A1 | NOVEL BENZOFURAN DERIVATIVES | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2003-02-12 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030149079-A1 | Novel benzofuran derivatives | CYP17A1, CYP21A2, HSD17B7 | CYP2A6 92/4885CYP3A4 82/4885CYP2C9 103/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.