Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.47 |
| ▸ | PPARG | P37231 | 1/20 | 0.47 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.46 |
| ▸ | ADORA1 | P30542 | 8/20 | 0.44 |
| ▸ | ADORA2A | P29274 | 6/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | GRM6 | O15303 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11948735 | 0.78 | ADORA1 (0.47) | ALDH1A1KDM4ELMNAADORA1ADORA2A | |
| SCHEMBL12285001 | 0.76 | NPC1 (0.56) | RXFP1ALDH1A1ADORA1ADORA2AMEN1 | |
| SCHEMBL5154549 | 0.75 | ADORA1 (0.47) | RXFP1ALDH1A1ADORA1ADORA2AMEN1 | |
| SCHEMBL5150675 | 0.75 | ADORA1 (0.56) | ADORA1ADORA2AGRM6HSD17B10ADORA2B | |
| SCHEMBL19665219 | 0.71 | RXFP1 (0.64) | RXFP1PPARGNCOR2ALDH1A1KDM4E | |
| SCHEMBL29349579 | 0.71 | KMT2A (0.51) | RXFP1PPARGNCOR2ALDH1A1KDM4E | |
| SCHEMBL30852637 | 0.71 | GRIA4 (0.46) | ALDH1A1GRIA4ADORA1ADORA2AMEN1 | |
| SCHEMBL1808677 | 0.70 | PLA2G1B (0.52) | ALDH1A1KDM4EADORA1ADORA2AMAPT | |
| SCHEMBL11443695 | 0.70 | ALDH1A1 (0.47) | ALDH1A1KDM4ELMNAGRIA4MAPK1 | |
| SCHEMBL5638835 | 0.70 | ALDH1A1 (0.59) | RXFP1ALDH1A1KDM4ELMNAMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040023807-A1 | 3-Arylisothiazoles and their use as herbicides | BASF AKTIENGESELLSCHAFT (DE) | 2004-02-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040023807-A1 | 3-Arylisothiazoles and their use as herbicides | DDT, HAX1, SULT1E1 | RXFP1 341/4885PPARG 607/4885NCOR2 1661/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.