Known targets — ChEMBL curated mechanism
SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9A
The experimentally established mechanism targets of Gluconic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 1/20 | 0.59 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | FKBP5 | Q13451 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Gluconic Acid SCHEMBL28696571 | 1.00 | PDE4A (0.59) | PDE4ALMNAALDH1A1FKBP5USP2 | |
| Gluconic Acid SCHEMBL28694334 | 0.87 | PDE4A (0.45) | PDE4ALMNAALDH1A1FKBP5USP2 | |
| Gluconic Acid SCHEMBL29067062 | 0.86 | PDE4A (0.44) | PDE4ALMNAL3MBTL1CYP2C9KDM4E | |
| Cadaverine Tartrate SCHEMBL7571787 | 0.81 | ALDH1A1 (0.56) | ALDH1A1FKBP5TSHRKDM4E | |
| Cadaverine Tartrate SCHEMBL5241549 | 0.81 | ALDH1A1 (0.56) | ALDH1A1FKBP5TSHRKDM4E | |
| Imidazole SCHEMBL10691122 | 0.78 | OR51E2 (0.52) | ALDH1A1FKBP5KDM4E | |
| Gluconic Acid SCHEMBL28769290 | 0.78 | PDE4A (0.70) | PDE4ALMNAUSP2SLCO1B1L3MBTL1 | |
| Gluconic Acid SCHEMBL28705777 | 0.77 | PDE4A (0.91) | PDE4ALMNAALDH1A1USP2SLCO1B1 | |
| Gluconic Acid SCHEMBL27479225 | 0.77 | PDE4A (0.91) | PDE4ALMNAUSP2SLCO1B1L3MBTL1 | |
| Gluconic Acid SCHEMBL8462892 | 0.77 | PDE4A (1.00) | PDE4ALMNAALDH1A1USP2SLCO1B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6692911-B2 | Cell delivery compositions | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 2004-02-17 | — | — | US | disclosed |
| US-20010006817-A1 | CELL DELIVERY COMPOSITIONS | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2001-07-05 | — | — | US | disclosed |