Imidazole

Imidazole

SCHEMBL10691122

O=C(O)C(O)CO.c1c[nH]cn1

nearest known ligand 0.52

Full drug profile on Sugi Atlas →

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
OR51E2 Q9H255 1/20 0.52
ALDH1A1 P00352 1/20 0.48
FKBP5 Q13451 1/20 0.48
TBXAS1 P24557 2/20 0.34
PTPRA P18433 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.31
KDM4E B2RXH2 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Malic Acid SCHEMBL1646346 0.84 SMN1; SMN2 (0.54) OR51E2ALDH1A1FKBP5TBXAS1PTPRA
Cadaverine Tartrate SCHEMBL7571787 0.80 ALDH1A1 (0.56) ALDH1A1FKBP5KDM4E
Cadaverine Tartrate SCHEMBL5241549 0.80 ALDH1A1 (0.56) ALDH1A1FKBP5KDM4E
Serine SCHEMBL424445 0.80 ALDH1A1 (0.46) ALDH1A1FKBP5
Serine SCHEMBL424443 0.80 ALDH1A1 (0.46) ALDH1A1FKBP5
Lactic Acid SCHEMBL1331765 0.79 ALDH1A1 (0.54) ALDH1A1FKBP5
Gluconic Acid SCHEMBL6741246 0.78 PDE4A (0.59) ALDH1A1FKBP5KDM4E
Gluconic Acid SCHEMBL28696571 0.78 PDE4A (0.59) ALDH1A1FKBP5KDM4E
Glycerin SCHEMBL23579100 0.78 ALDH1A1 (0.59) ALDH1A1FKBP5
Glycerin SCHEMBL231119 0.78 ALDH1A1 (0.59) ALDH1A1FKBP5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0252774-A1 Saccharomyces strains producing alpha-amylase TRANSGENE S.A. (FR) 1988-01-13 EP disclosed