SCHEMBL674127

SCHEMBL674127

CC(C)(C)OC(=O)NCCOCCO

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.61
MEN1 O00255 2/20 0.49
KMT2A Q03164 2/20 0.49
GAA P10253 1/20 0.49
CA12 O43570 6/20 0.46
CA1 P00915 6/20 0.46
CA2 P00918 6/20 0.46
CA9 Q16790 6/20 0.46
MAOA P21397 1/20 0.45
MAOB P27338 1/20 0.45
IDO1 P14902 1/20 0.43
EPHX1 P07099 1/20 0.43
ACHE P22303 1/20 0.41
ALDH1A1 P00352 1/20 0.40
BCHE P06276 1/20 0.40
CNR2 P34972 1/20 0.40
HTT P42858 1/20 0.39
NPSR1 Q6W5P4 1/20 0.39
ADRB2 P07550 1/20 0.39
HTR1A P08908 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27333054 0.98 TDP1 (0.59) TDP1MEN1KMT2AGAACA12
SCHEMBL26101468 0.98 TDP1 (0.59) TDP1MEN1KMT2AGAACA12
SCHEMBL10491984 0.98 TDP1 (0.59) TDP1MEN1KMT2AGAACA12
SCHEMBL30056089 0.98 TDP1 (0.59) TDP1MEN1KMT2AGAACA12
SCHEMBL114816 0.98 TDP1 (0.59) TDP1MEN1KMT2AGAACA12
SCHEMBL23728653 0.98 TDP1 (0.59) TDP1MEN1KMT2AGAACA12
SCHEMBL31395855 0.98 TDP1 (0.59) TDP1MEN1KMT2AGAACA12
SCHEMBL30537805 0.98 TDP1 (0.59) TDP1MEN1KMT2AGAACA12
SCHEMBL18365027 0.98 TDP1 (0.59) TDP1MEN1KMT2AGAACA12
SCHEMBL995743 0.98 TDP1 (0.59) TDP1MEN1KMT2AGAACA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 986 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114452404-B Vesicle with anchoring and charge overturning functions and preparation and application thereof 中山大学附属第三医院(中山大学肝脏病医院) 2023-09-08 CN claimed
CN-114452404-A Vesicle with anchoring and charge reversing functions and preparation and application thereof 中山大学附属第三医院(中山大学肝脏病医院) 2022-05-10 CN claimed
EP-4747260-A1 MACROCYCLES FOR THE TREATMENT OF AUTOIMMUNE DISEASE F. Hoffmann-La Roche AG (CH) 2026-05-27 EP disclosed
EP-3972649-B1 MCL-1 INHIBITOR ANTIBODY-DRUG CONJUGATES AND METHODS OF USE NOVARTIS AG (CH) 2026-05-13 EP disclosed
US-12622944-B2 Compositions containing, methods involving, and uses of non-natural amino acid linked dolastatin derivatives AMBRX, INC. (US) 2026-05-12 US disclosed
EP-4731611-A1 TARGETED DEGRADERS OF HIV-1 NEF FOR THE TREATMENT OF HIV DISEASE UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) 2026-04-29 EP disclosed
US-20260108618-A1 COMPOSITIONS AND METHODS FOR THE TREATMENT OF VIRAL INFECTIONS CIDARA THERAPEUTICS, INC. 2026-04-23 US disclosed
EP-4727537-A2 SIGLEC LIGANDS, CONJUGATES, AND METHODS OF USE THEREOF Adaxion Therapeutics, Inc. (US) 2026-04-22 EP disclosed
EP-3886904-B1 IRAK DEGRADERS AND USES THEREOF KYMERA THERAPEUTICS INC (US) 2026-04-22 EP disclosed
US-12583900-B2 Peptide conjugates and methods of use THE SCRIPPS RESEARCH INSTITUTE (US) 2026-03-24 US disclosed
EP-4705299-A1 RADIOPHARMACEUTICAL COMPOSITIONS TARGETING CARBONIC ANHYDRASE IX AND USES THEREOF Rayzebio, Inc. (US) 2026-03-11 EP disclosed
US-6171520-B1 Reagents for labeling SH groups, process for the preparation of them and method for labeling with them SS PHARMACEUTICAL CO., LTD. (JP) 2001-01-09 US disclosed
WO-2000061561-A1 CYANOGUANIDINE COMPOUNDS SHIONOGI BIORESEARCH CORP. (US) 2000-10-19 WO disclosed
US-5773612-A VASOPRESSIN OR OXYTOCIN RECEPTORS SANOFI (FR) 1998-06-30 US disclosed
EP-0844246-A1 REAGENTS FOR LABELING SH GROUPS, PROCESS FOR THE PREPARATION OF THEM, AND METHOD FOR LABELING WITH THEM SS Pharmaceutical Co., Ltd. (JP) 1998-05-27 EP disclosed
WO-1997020821-A1 HETEROARYL DERIVATIVES NOVARTIS AG (CH) 1997-06-12 WO disclosed
US-5594023-A 1,3-dihydroindol-2-one derivatives substituted in the 3-position by a nitrogen-containing group, their preparation and the pharmaceutical compositions in which they are present SANOFI (FR) 1997-01-14 US disclosed
EP-0687251-A1 1,3-DIHYDROINDOL-2-ONE DERIVATIVES SUBSTITUTED IN POSITION 3 BY A NITROGEN GROUP AS VASOPRESSIN AND/OR OCYTOCINE AGONISTS AND/OR ANTAGONISTS SANOFI (FR) 1995-12-20 EP disclosed
WO-1995018105-A1 1,3-DIHYDROINDOL-2-ONE DERIVATIVES SUBSTITUTED IN POSITION 3 BY A NITROGEN GROUP AS VASOPRESSIN AND/OR OCYTOCINE AGONISTS AND/OR ANTAGONISTS SANOFI (FR) 1995-07-06 WO disclosed
US-5144043-A Coupling protein or peptide to radionucleotide; labeling antibodies CENTOCOR (US) 1992-09-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12583900-B2 Peptide conjugates and methods of use GIPR, GLP1R, GCG TDP1 3652/4885MEN1 221/4885KMT2A 1061/4885
US-12622944-B2 Compositions containing, methods involving, and uses of non-natural amino acid linked dolastatin derivatives DDOST, DMPK, KRTCAP2 TDP1 4012/4885MEN1 4217/4885KMT2A 2934/4885
US-20260108618-A1 COMPOSITIONS AND METHODS FOR THE TREATMENT OF VIRAL INFECTIONS FCGR3B, FCGR1A, FCGR2A TDP1 3694/4885MEN1 4679/4885KMT2A 1692/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.