Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.53 |
| ▸ | TSHR | P16473 | 6/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | PHGDH | O43175 | 1/20 | 0.43 |
| ▸ | MGLL | Q99685 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20094631 | 0.80 | SIGMAR1 (0.49) | SIGMAR1TSHRMEN1KMT2APHGDH | |
| SCHEMBL6743387 | 0.77 | SIGMAR1 (0.46) | SIGMAR1TSHRMEN1KMT2APHGDH | |
| SCHEMBL12858869 | 0.77 | HRH3 (0.53) | SIGMAR1TSHRMEN1KMT2APHGDH | |
| SCHEMBL8186259 | 0.77 | HRH3 (0.53) | SIGMAR1TSHRMEN1KMT2APHGDH | |
| SCHEMBL24302231 | 0.75 | PHGDH (0.56) | SIGMAR1MEN1KMT2APHGDHMGLL | |
| SCHEMBL584039 | 0.75 | — | — | |
| SCHEMBL5784736 | 0.75 | PHGDH (0.56) | SIGMAR1MEN1KMT2APHGDHMGLL | |
| SCHEMBL6664812 | 0.75 | PHGDH (0.56) | SIGMAR1MEN1KMT2APHGDHMGLL | |
| SCHEMBL6245189 | 0.75 | PHGDH (0.56) | SIGMAR1MEN1KMT2APHGDHMGLL | |
| SCHEMBL9695357 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6689919-B1 | SOLUBLE POLY(OXYFLUOROPHENYLENE) COMPOUNDS WITH EXCELLENT HEAT RESISTANCE, MEMBRANE-FORMABILITY AND CHEMICAL STABILITY | JAPAN SCIENCE AND TECHNOLOGY CORPORATION (JP) | 2004-02-10 | — | — | US | disclosed |