Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.46 |
| ▸ | CHRM2 | P08172 | 7/20 | 0.44 |
| ▸ | CHRM1 | P11229 | 7/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | PHGDH | O43175 | 1/20 | 0.42 |
| ▸ | MGLL | Q99685 | 1/20 | 0.42 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.42 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.42 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12858869 | 0.86 | HRH3 (0.53) | SIGMAR1CHRM2CHRM1TP53PHGDH | |
| SCHEMBL8186259 | 0.86 | HRH3 (0.53) | SIGMAR1CHRM2CHRM1TP53PHGDH | |
| SCHEMBL10092689 | 0.84 | HRH3 (0.50) | SIGMAR1CHRM2CHRM1TP53PHGDH | |
| SCHEMBL28639866 | 0.83 | SIGMAR1 (0.47) | SIGMAR1CHRM2CHRM1TP53PHGDH | |
| SCHEMBL21361601 | 0.80 | SIGMAR1 (0.41) | SIGMAR1CHRM2CHRM1TP53PHGDH | |
| SCHEMBL24302231 | 0.80 | PHGDH (0.56) | SIGMAR1PHGDHMGLLMEN1KMT2A | |
| SCHEMBL584039 | 0.80 | — | — | |
| SCHEMBL5784736 | 0.80 | PHGDH (0.56) | SIGMAR1PHGDHMGLLMEN1KMT2A | |
| SCHEMBL6664812 | 0.80 | PHGDH (0.56) | SIGMAR1PHGDHMGLLMEN1KMT2A | |
| SCHEMBL6245189 | 0.80 | PHGDH (0.56) | SIGMAR1PHGDHMGLLMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6689919-B1 | SOLUBLE POLY(OXYFLUOROPHENYLENE) COMPOUNDS WITH EXCELLENT HEAT RESISTANCE, MEMBRANE-FORMABILITY AND CHEMICAL STABILITY | JAPAN SCIENCE AND TECHNOLOGY CORPORATION (JP) | 2004-02-10 | — | — | US | disclosed |