Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 2/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.44 |
| ▸ | KCNQ3 | O43525 | 2/20 | 0.40 |
| ▸ | KCNQ2 | O43526 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | ALDH5A1 | P51649 | 1/20 | 0.35 |
| ▸ | ABAT | P80404 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | FABP7 | O15540 | 1/20 | 0.35 |
| ▸ | FABP3 | P05413 | 1/20 | 0.35 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6737724 | 1.00 | SLC6A2 (0.44) | SLC6A2SLC6A4KCNQ3KCNQ2ALDH1A1 | |
| SCHEMBL901089 | 0.81 | SLC6A2 (0.48) | SLC6A2SLC6A4KCNQ3KCNQ2ALDH1A1 | |
| SCHEMBL7352068 | 0.80 | KCNQ3 (0.53) | SLC6A2SLC6A4KCNQ3KCNQ2ALDH1A1 | |
| SCHEMBL839092 | 0.80 | KCNQ3 (0.53) | SLC6A2SLC6A4KCNQ3KCNQ2ALDH1A1 | |
| SCHEMBL4522521 | 0.80 | KCNQ3 (0.53) | SLC6A2SLC6A4KCNQ3KCNQ2ALDH1A1 | |
| SCHEMBL7352063 | 0.80 | KCNQ3 (0.53) | SLC6A2SLC6A4KCNQ3KCNQ2ALDH1A1 | |
| SCHEMBL12592455 | 0.80 | KCNQ3 (0.53) | SLC6A2SLC6A4KCNQ3KCNQ2ALDH1A1 | |
| SCHEMBL838634 | 0.80 | KCNQ3 (0.56) | SLC6A2SLC6A4KCNQ3KCNQ2ALDH1A1 | |
| SCHEMBL22492058 | 0.80 | KCNQ3 (0.56) | SLC6A2SLC6A4KCNQ3KCNQ2ALDH1A1 | |
| SCHEMBL22492062 | 0.80 | KCNQ3 (0.56) | SLC6A2SLC6A4KCNQ3KCNQ2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040235830-A1 | Substituted cyclohexane derivatives and the use thereof in medicaments for treating cardiovascular diseases | BAYER AKTIENGESELLSCHAFT (DE) | 2004-11-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040235830-A1 | Substituted cyclohexane derivatives and the use thereof in medicaments for treating cardiovascular diseases | CYP46A1, REN, CYP11B2 | SLC6A2 1559/4885SLC6A4 3069/4885KCNQ3 3634/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.